Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.37 |
| ▸ | PI4KA | P42356 | 1/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.36 |
| ▸ | DCUN1D1 | Q96GG9 | 2/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | CCR2 | P41597 | 1/20 | 0.36 |
| ▸ | ALB | P02768 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4737498 | 0.92 | PI4KA (0.39) | PI4KAPIK3CGPIK3CAPIK3CDMAPT | |
| SCHEMBL4736827 | 0.88 | CCR2 (0.40) | PI4KAPIK3CGPIK3CAPIK3CDCCR2 | |
| SCHEMBL4741753 | 0.88 | CCR2 (0.42) | PI4KAPIK3CGPIK3CAPIK3CDCCR2 | |
| SCHEMBL4740771 | 0.86 | CCR2 (0.38) | PI4KAPIK3CGPIK3CAPIK3CDCCR2 | |
| SCHEMBL4739014 | 0.85 | PI4KA (0.42) | PI4KAPIK3CGPIK3CAPIK3CDCCR2 | |
| SCHEMBL4787508 | 0.84 | PIK3CD (0.44) | PI4KAPIK3CGPIK3CAPIK3CDCCR2 | |
| SCHEMBL4740778 | 0.83 | CCR2 (0.39) | PI4KAPIK3CGPIK3CAPIK3CDCCR2 | |
| SCHEMBL4785896 | 0.83 | ADORA2A (0.41) | PI4KAPIK3CGPIK3CAPIK3CDCCR2 | |
| SCHEMBL4787625 | 0.82 | PIK3CA (0.42) | PI4KAPIK3CGGAAKDM4EPIK3CA | |
| SCHEMBL14148281 | 0.82 | PIK3CA (0.48) | PIK3CGPIK3CAPIK3CDCCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008086158-A1 | BENZODIHYDROQUINAZOLINE AS PI3 KINASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2008-07-17 | — | — | WO | disclosed |
| WO-2008086158-A1 | BENZODIHYDROQUINAZOLINE AS PI3 KINASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2008-07-17 | — | — | WO | disclosed |