Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.80 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.80 |
| ▸ | HPGD | P15428 | 4/20 | 0.80 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.80 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.80 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.80 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.80 |
| ▸ | TP53 | P04637 | 1/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4734522 | 0.91 | ALDH1A1 (0.80) | ALDH1A1KDM4EHPGDCYP1A2CYP3A4 | |
| SCHEMBL4732913 | 0.88 | KDM4E (1.00) | ALDH1A1KDM4EHPGDCYP1A2CYP3A4 | |
| SCHEMBL4733114 | 0.84 | ALDH1A1 (0.58) | ALDH1A1KDM4EHPGDCYP1A2CYP3A4 | |
| SCHEMBL4735940 | 0.83 | KDM4E (0.56) | ALDH1A1KDM4EHPGDCYP1A2CYP3A4 | |
| SCHEMBL4735039 | 0.82 | L3MBTL1 (0.56) | ALDH1A1KDM4EHPGDCYP1A2CYP3A4 | |
| SCHEMBL4737108 | 0.82 | POLB (0.59) | ALDH1A1KDM4EHPGDCYP1A2CYP3A4 | |
| SCHEMBL4732905 | 0.81 | L3MBTL1 (0.81) | ALDH1A1KDM4ECYP1A2CYP3A4CYP2C9 | |
| SCHEMBL4734776 | 0.79 | ALDH1A1 (1.00) | ALDH1A1KDM4EHPGDCYP1A2CYP3A4 | |
| SCHEMBL4734500 | 0.78 | L3MBTL1 (0.50) | ALDH1A1KDM4EHPGDCYP1A2CYP3A4 | |
| SCHEMBL4737371 | 0.76 | ALDH1A1 (0.56) | ALDH1A1KDM4EHPGDCYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008069611-A1 | N-PHENYLAMIDE DERIVATIVE, PROCESS FOR THE PREPARATION THEREOF, AND COMPOSITION FOR PREVENTING OR TREATING ISCHEMIC DISEASES COMPRISING SAME | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2008-06-12 | — | — | WO | claimed |
| WO-2008069611-A1 | N-PHENYLAMIDE DERIVATIVE, PROCESS FOR THE PREPARATION THEREOF, AND COMPOSITION FOR PREVENTING OR TREATING ISCHEMIC DISEASES COMPRISING SAME | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2008-06-12 | — | — | WO | disclosed |