Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.60 |
| ▸ | MEN1 | O00255 | 4/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | FPR2 | P25090 | 1/20 | 0.52 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 6/20 | 0.51 |
| ▸ | NPC1 | O15118 | 5/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | NAMPT | P43490 | 2/20 | 0.48 |
| ▸ | FAAH | O00519 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4739556 | 0.81 | MEN1 (0.58) | KMT2AMEN1MAPTPOLBALDH1A1 | |
| SCHEMBL27887140 | 0.80 | KMT2A (0.55) | KMT2AMEN1MAPTALDH1A1RAB9A | |
| SCHEMBL1690744 | 0.78 | FAAH (0.69) | KMT2AMEN1MAPTALDH1A1GAA | |
| SCHEMBL21382248 | 0.77 | KMT2A (0.57) | KMT2AMEN1RAB9ANPC1 | |
| SCHEMBL4769744 | 0.77 | KMT2A (0.57) | KMT2AMEN1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL7782533 | 0.76 | MAPT (0.79) | KMT2AMEN1MAPTPOLBALDH1A1 | |
| SCHEMBL7785670 | 0.76 | MAPT (0.79) | KMT2AMEN1MAPTPOLBALDH1A1 | |
| SCHEMBL8585756 | 0.76 | KMT2A (0.56) | KMT2AMEN1FPR2RAB9ANPC1 | |
| SCHEMBL7598228 | 0.76 | MAPT (0.73) | KMT2AMEN1MAPTPOLBALDH1A1 | |
| SCHEMBL5110887 | 0.75 | NPC1 (0.63) | KMT2AMEN1MAPTGAARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008086462-A2 | AMINO-SUBSTITUTED QUINAZOLINE DERIVATIVES AS INHIBITORS OF β-CANTENIN/TCF-4 PATHWAY AND CANCER TREATMENT AGENTS | WYETH (US) | 2008-07-17 | — | — | WO | disclosed |