Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 13/20 | 0.66 |
| ▸ | LMNA | P02545 | 9/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.66 |
| ▸ | HTT | P42858 | 5/20 | 0.66 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.66 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.66 |
| ▸ | FGB | P02675 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.54 |
| ▸ | GABRP | O00591 | 1/20 | 0.48 |
| ▸ | GABRD | O14764 | 1/20 | 0.48 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.48 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.48 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.48 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.48 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.48 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.48 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.48 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.48 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14270581 | 0.83 | MAPT (0.64) | MAPTLMNASMN1; SMN2HTTHSP90AA1 | |
| SCHEMBL4786063 | 0.82 | MAPT (0.51) | MAPTLMNASMN1; SMN2HTTHSP90AA1 | |
| SCHEMBL2806738 | 0.80 | MAPT (1.00) | MAPTLMNASMN1; SMN2HTTHSP90AA1 | |
| SCHEMBL2350732 | 0.80 | MAPT (1.00) | MAPTLMNASMN1; SMN2HTTHSP90AA1 | |
| Acetic Acid SCHEMBL7467661 | 0.76 | MAPT (0.92) | MAPTLMNASMN1; SMN2HTTHSP90AA1 | |
| SCHEMBL15111207 | 0.76 | MAPT (0.56) | MAPTLMNASMN1; SMN2HTTHSP90AA1 | |
| SCHEMBL9178589 | 0.75 | MAPT (0.51) | MAPTLMNASMN1; SMN2HTTHSP90AA1 | |
| SCHEMBL27848261 | 0.74 | MAPT (0.46) | MAPTLMNASMN1; SMN2HTTHSP90AA1 | |
| SCHEMBL8536893 | 0.73 | MAPT (0.52) | MAPTLMNASMN1; SMN2HTTHSP90AA1 | |
| SCHEMBL27396758 | 0.72 | MAPT (0.48) | MAPTLMNASMN1; SMN2HTTHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1330454-A4 | BENZOPYRANYL HETEROCYCLE DERIVATIVES, PROCESS FOR PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DONGBU HANNONG CHEMICAL CO LTD (KR) | 2008-03-19 | — | — | EP | disclosed |
| EP-1330454-A1 | BENZOPYRANYL HETEROCYCLE DERIVATIVES, PROCESS FOR PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Dongbu Hannong Chemical Co., Ltd. (KR) | 2003-07-30 | — | — | EP | disclosed |
| WO-2002030925-A1 | BENZOPYRANYL HETEROCYCLE DERIVATIVES, PROCESS FOR PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DONGBU HANNONG CHEMICAL CO., LTD (KR) | 2002-04-18 | — | — | WO | disclosed |