Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.52 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | FGB | P02675 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | GABRP | O00591 | 2/20 | 0.39 |
| ▸ | GABRD | O14764 | 2/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.39 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8537449 | 0.84 | LMNA (0.34) | MAPTLMNASMN1; SMN2HIF1AHSP90AA1 | |
| SCHEMBL8910413 | 0.84 | FGB (0.41) | MAPTLMNASMN1; SMN2HIF1AHSP90AA1 | |
| SCHEMBL8911552 | 0.76 | SMN1; SMN2 (0.36) | MAPTLMNASMN1; SMN2HIF1AHSP90AA1 | |
| SCHEMBL8150303 | 0.74 | MAPT (0.41) | MAPTLMNASMN1; SMN2HIF1AHSP90AA1 | |
| SCHEMBL4738113 | 0.73 | MAPT (0.66) | MAPTLMNASMN1; SMN2HIF1AHSP90AA1 | |
| SCHEMBL7963227 | 0.72 | LMNA (0.36) | MAPTLMNASMN1; SMN2HIF1AHSP90AA1 | |
| SCHEMBL7966334 | 0.71 | KDM4E (0.36) | MAPTLMNASMN1; SMN2HIF1AHSP90AA1 | |
| SCHEMBL9434365 | 0.70 | FGB (0.42) | MAPTLMNASMN1; SMN2HIF1AHSP90AA1 | |
| SCHEMBL2806738 | 0.69 | MAPT (1.00) | MAPTLMNASMN1; SMN2HIF1AHSP90AA1 | |
| SCHEMBL2350732 | 0.69 | MAPT (1.00) | MAPTLMNASMN1; SMN2HIF1AHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5770598-A | ANTITUMOR AGENTS; REACTING WITH CARBONYL DIIMIDAZOLE AND AMIDOXIMES | UNIVERSITY COLLEGE CARDIFF CONSULTANTS LIMITED (GB) | 1998-06-23 | — | — | US | disclosed |