SCHEMBL4738270

SCHEMBL4738270

O=C(O)C=CC(=O)Nc1ccc(O)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 4/20 1.00
▸ L3MBTL1 Q9Y468 2/20 1.00
▸ TDP2 O95551 1/20 1.00
▸ GAA P10253 1/20 1.00
▸ THRB P10828 1/20 1.00
▸ LPAR2 Q9HBW0 2/20 0.75
▸ LPAR3 Q9UBY5 1/20 0.75
▸ NMT1 P30419 1/20 0.70
▸ ALDH1A1 P00352 10/20 0.68
▸ KDM4E B2RXH2 1/20 0.68
▸ POLB P06746 1/20 0.68
▸ SMN1; SMN2 Q16637 1/20 0.68
▸ MMP1 P03956 3/20 0.65
▸ MMP2 P08253 3/20 0.65
▸ MMP9 P14780 3/20 0.65
▸ KMT2A Q03164 2/20 0.64
▸ LMNA P02545 1/20 0.64
▸ NR4A1 P22736 1/20 0.64
▸ MEN1 O00255 1/20 0.64
▸ DEGS1 O15121 1/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4738261 1.00 MAPT (1.00) MAPTL3MBTL1TDP2GAATHRB
SCHEMBL5177071 1.00 MAPT (1.00) MAPTL3MBTL1TDP2GAATHRB
SCHEMBL8399691 0.98 MAPT (0.96) MAPTL3MBTL1TDP2GAATHRB
SCHEMBL8397647 0.98 MAPT (0.96) MAPTL3MBTL1TDP2GAATHRB
SCHEMBL7771152 0.92 MAPT (0.84) MAPTL3MBTL1TDP2GAATHRB
SCHEMBL11137034 0.92 LPAR2 (0.88) MAPTL3MBTL1TDP2GAATHRB
SCHEMBL11133691 0.92 LPAR2 (0.88) MAPTL3MBTL1TDP2GAATHRB
SCHEMBL7771158 0.92 MAPT (0.84) MAPTL3MBTL1TDP2GAATHRB
SCHEMBL22862151 0.90 MAPT (0.81) MAPTL3MBTL1TDP2GAATHRB
SCHEMBL22862154 0.90 MAPT (0.81) MAPTL3MBTL1TDP2GAATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117854869-A Iron-based nanocrystalline soft magnetic composite material with low iron loss and preparation method thereof 朗峰新材料启东有限公司 2024-04-09 — — CN claimed
EP-0372922-B1 Preparation process of N-substituted maleimides MITSUI TOATSU CHEMICALS (JP) 1994-03-09 — — EP claimed
US-5175309-A Forming an imide by heat catalytic dehydration MITSUI TOATSU CHEMICALS INC. (JP) 1992-12-29 — — US claimed
EP-0372922-A2 Preparation process of N-substituted maleimides MITSUI TOATSU CHEMICALS, Inc. (JP) 1990-06-13 — — EP claimed
CN-118271728-A High-strength thermoplastic resin for fan blades and preparation method thereof 北京理工大学珠海学院 2024-07-02 — — CN disclosed
CN-117854869-A Iron-based nanocrystalline soft magnetic composite material with low iron loss and preparation method thereof 朗峰新材料启东有限公司 2024-04-09 — — CN disclosed
CN-117854869-A Iron-based nanocrystalline soft magnetic composite material with low iron loss and preparation method thereof 朗峰新材料启东有限公司 2024-04-09 — — CN disclosed
WO-2008082108-A1 ORGANIC COPOLYMER FOR PREPARING ORGANIC ANTIREFLECTIVE COATING, METHOD OF PREPARING THE SAME, AND COMPOSITION COMPRISING THE SAME HYOSUNG CORPORATION (KR) 2008-07-10 — — WO disclosed
US-20040110256-A1 Method of decomposing unsaturated carboxylic acid copolymer IDEMITSU KOSAN CO. LTD. (JP) 2004-06-10 — — US disclosed
EP-1382671-A1 METHOD OF DECOMPOSING UNSATURATED CARBOXYLIC ACID COPOLYMER IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2004-01-21 — — EP disclosed
JP-2003064133-A BIODEGRADABLE POLYMER AND METHOD FOR PRODUCING THE SAME IDEMITSU PETROCHEM CO LTD 2003-03-05 — — JP disclosed
EP-0850919-B1 Rosinate esters of n-hydroxyphenyl maleamic acid GOODYEAR TIRE & RUBBER (US) 2002-02-06 — — EP disclosed
EP-0403240-A1 Preparation process of N-substituted maleimides MITSUI TOATSU CHEMICALS, Inc. (JP) 1990-12-19 — — EP disclosed
EP-0372922-A2 Preparation process of N-substituted maleimides MITSUI TOATSU CHEMICALS, Inc. (JP) 1990-06-13 — — EP disclosed
US-4816523-A LIGHT SENSITIVE ELEMENTS UBE INDUSTRIES, LTD. (JP) 1989-03-28 — — US disclosed
US-4740561-A MALEIC ANHYDRIDE UNSATURATED HYDROCARBON COPOLYMER REACTED WITH AMINOPHENOL UBE INDUSTRIES, LTD. (JP) 1988-04-26 — — US disclosed
US-4581461-A Maleated siloxane derivatives NATIONAL STARCH AND CHEMICAL CORPORATION (US) 1986-04-08 — — US disclosed
US-4289699-A DISSOLVING CORRESPONSING ESTER IN OXYACID, HYDROLYSIS, PRECIPITATION MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1981-09-15 — — US disclosed
US-4231934-A TREATING A N-(HYDROXYPHENYL)MALEAMIC ACID WITH A DEHYDRATING AGENT MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1980-11-04 — — US disclosed
US-4130564-A CYCLODEHYDRATION CIBA-GEIGY CORPORATION (US) 1978-12-19 — — US disclosed
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