SCHEMBL5177071

SCHEMBL5177071

O=C(O)/C=C/C(=O)Nc1ccc(O)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 4/20 1.00
▸ L3MBTL1 Q9Y468 2/20 1.00
▸ TDP2 O95551 1/20 1.00
▸ GAA P10253 1/20 1.00
▸ THRB P10828 1/20 1.00
▸ LPAR2 Q9HBW0 2/20 0.75
▸ LPAR3 Q9UBY5 1/20 0.75
▸ NMT1 P30419 1/20 0.70
▸ ALDH1A1 P00352 10/20 0.68
▸ KDM4E B2RXH2 1/20 0.68
▸ POLB P06746 1/20 0.68
▸ SMN1; SMN2 Q16637 1/20 0.68
▸ MMP1 P03956 3/20 0.65
▸ MMP2 P08253 3/20 0.65
▸ MMP9 P14780 3/20 0.65
▸ KMT2A Q03164 2/20 0.64
▸ LMNA P02545 1/20 0.64
▸ NR4A1 P22736 1/20 0.64
▸ MEN1 O00255 1/20 0.64
▸ DEGS1 O15121 1/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4738261 1.00 MAPT (1.00) MAPTL3MBTL1TDP2GAATHRB
SCHEMBL4738270 1.00 MAPT (1.00) MAPTL3MBTL1TDP2GAATHRB
SCHEMBL8399691 0.98 MAPT (0.96) MAPTL3MBTL1TDP2GAATHRB
SCHEMBL8397647 0.98 MAPT (0.96) MAPTL3MBTL1TDP2GAATHRB
SCHEMBL7771152 0.92 MAPT (0.84) MAPTL3MBTL1TDP2GAATHRB
SCHEMBL11137034 0.92 LPAR2 (0.88) MAPTL3MBTL1TDP2GAATHRB
SCHEMBL11133691 0.92 LPAR2 (0.88) MAPTL3MBTL1TDP2GAATHRB
SCHEMBL7771158 0.92 MAPT (0.84) MAPTL3MBTL1TDP2GAATHRB
SCHEMBL22862151 0.90 MAPT (0.81) MAPTL3MBTL1TDP2GAATHRB
SCHEMBL22862154 0.90 MAPT (0.81) MAPTL3MBTL1TDP2GAATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1602481-B1 Lithographic printing plate precursor FUJIFILM CORP (JP) 2007-05-30 — — EP disclosed
EP-1203659-B1 Lithographic printing plate precursor FUJI PHOTO FILM CO LTD (JP) 2006-05-17 — — EP disclosed
EP-1602481-A1 Lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2005-12-07 — — EP disclosed
US-6939658-B2 Lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2005-09-06 — — US disclosed
EP-1048457-B1 Lithographic printing plate precursor FUJI PHOTO FILM CO LTD (JP) 2004-12-15 — — EP disclosed
US-6824946-B2 SUPPORT WITH HYDROPHILIC SURFACE HAVING AN IMAGE-FORMING LAYER CONTAINING A HYDROPHOBIC HIGH MOLECULAR COMPOUND WITH SALTS OF SULFONATES AND CARBOXYLS WITH IODONIUM, SULFONIUM OR DIAZONIUM IONS FUJI PHOTO FILM CO., LTD. (JP) 2004-11-30 — — US disclosed
EP-1031414-B1 Lithographic printing plate precursor FUJI PHOTO FILM CO LTD (JP) 2004-06-16 — — EP disclosed
US-20040110256-A1 Method of decomposing unsaturated carboxylic acid copolymer IDEMITSU KOSAN CO. LTD. (JP) 2004-06-10 — — US disclosed
US-20040086799-A1 Lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2004-05-06 — — US disclosed
EP-1382671-A1 METHOD OF DECOMPOSING UNSATURATED CARBOXYLIC ACID COPOLYMER IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2004-01-21 — — EP disclosed
US-6680161-B2 Lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2004-01-20 — — US disclosed
US-6509132-B1 Comprises an ink-receptive image area for receiving ink during the printing process and a hydrophilic non-image area for receiving fountain solution FUJI PHOTO FILM CO., LTD. (JP) 2003-01-21 — — US disclosed
US-6455224-B1 SUPPORT WITH HYDROPHILIC SURFACE AND PHOTOSENSITIVE LAYER CONTAINING INFRARED ABSORBENT WHICH CHANGES FROM HYDROPHILIC TO HYDROPHOBIC BY HEAT AND HYDROPHILIC POLYMER HAVING FUNCTIONAL GROUP RENDERING LAYER WATER DEVELOPABLE FUJI PHOTO FILM CO., LTD. (JP) 2002-09-24 — — US disclosed
US-20020068241-A1 Lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2002-06-06 — — US disclosed
EP-1203659-A2 Lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2002-05-08 — — EP disclosed
EP-1048457-A2 Lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2000-11-02 — — EP disclosed
EP-1031414-A1 Lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2000-08-30 — — EP disclosed
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