Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.96 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.96 |
| ▸ | TDP2 | O95551 | 1/20 | 0.96 |
| ▸ | GAA | P10253 | 1/20 | 0.96 |
| ▸ | THRB | P10828 | 1/20 | 0.96 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.72 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.72 |
| ▸ | NMT1 | P30419 | 1/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.66 |
| ▸ | POLB | P06746 | 1/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.66 |
| ▸ | MMP1 | P03956 | 3/20 | 0.62 |
| ▸ | MMP2 | P08253 | 3/20 | 0.62 |
| ▸ | MMP9 | P14780 | 3/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4738270 | 0.98 | MAPT (1.00) | MAPTL3MBTL1TDP2GAATHRB | |
| SCHEMBL5177071 | 0.98 | MAPT (1.00) | MAPTL3MBTL1TDP2GAATHRB | |
| SCHEMBL4738261 | 0.98 | MAPT (1.00) | MAPTL3MBTL1TDP2GAATHRB | |
| SCHEMBL8397647 | 0.96 | MAPT (0.96) | MAPTL3MBTL1TDP2GAATHRB | |
| SCHEMBL7771152 | 0.90 | MAPT (0.84) | MAPTL3MBTL1TDP2GAATHRB | |
| SCHEMBL11137034 | 0.90 | LPAR2 (0.88) | MAPTL3MBTL1TDP2GAATHRB | |
| SCHEMBL11133691 | 0.90 | LPAR2 (0.88) | MAPTL3MBTL1TDP2GAATHRB | |
| SCHEMBL7771158 | 0.90 | MAPT (0.84) | MAPTL3MBTL1TDP2GAATHRB | |
| SCHEMBL22862154 | 0.88 | MAPT (0.81) | MAPTL3MBTL1TDP2GAATHRB | |
| SCHEMBL22862151 | 0.88 | MAPT (0.81) | MAPTL3MBTL1TDP2GAATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5872167-A | IMPROVED PEEL ADHESION | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1999-02-16 | — | — | US | disclosed |