Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 19/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | CGAS | Q8N884 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4799779 | 0.85 | HRH4 (0.49) | HRH4HRH3 | |
| SCHEMBL4786925 | 0.81 | HRH4 (0.41) | HRH4HRH3 | |
| SCHEMBL4786930 | 0.77 | HRH4 (0.41) | HRH4 | |
| SCHEMBL4594250 | 0.69 | HRH4 (0.65) | HRH4HRH3 | |
| SCHEMBL4594254 | 0.69 | HRH4 (0.65) | HRH4HRH3 | |
| SCHEMBL4595498 | 0.69 | HRH4 (0.68) | HRH4HRH3 | |
| SCHEMBL4595075 | 0.69 | HRH4 (0.68) | HRH4HRH3 | |
| SCHEMBL604593 | 0.69 | HRH4 (0.72) | HRH4HRH3 | |
| SCHEMBL4740059 | 0.68 | HRH4 (0.65) | HRH4HRH3 | |
| SCHEMBL1534427 | 0.67 | NOTUM (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008074445-A1 | NOVEL TRICYCLIC AND HETEROTRICYCLIC DERIVATIVES, PROCESSES FOR PREPARING THEM, PHARMACEUTICAL COMPOSITIONS THEREOF | UCB PHARMA, S.A. (BE) | 2008-06-26 | — | — | WO | disclosed |