Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 2/20 | 0.40 |
| ▸ | PPARA | Q07869 | 2/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4738384 | 0.85 | CYP2C9 (0.46) | CYP2C9TSHRLTA4HPPARAHRH3 | |
| SCHEMBL11793369 | 0.82 | ALDH1A1 (0.43) | CYP2C9TSHRLMNAMAPTPOLB | |
| SCHEMBL2140259 | 0.81 | PPARA (0.42) | CYP2C9TSHRLTA4HPPARGPPARA | |
| SCHEMBL11563229 | 0.80 | PTGS1 (0.50) | CYP2C9TSHRLTA4HADRB2ADRB1 | |
| SCHEMBL8048422 | 0.80 | MAPT (0.53) | CYP2C9LTA4HLMNAMAPTPOLB | |
| SCHEMBL7931690 | 0.79 | CYP2C9 (0.60) | CYP2C9TSHRMAPTPOLBMEN1 | |
| SCHEMBL12129217 | 0.79 | CYP2C9 (0.44) | CYP2C9TSHRLTA4HPPARGPPARA | |
| SCHEMBL1628642 | 0.78 | LMNA (0.62) | CYP2C9TSHRLTA4HPPARGPPARA | |
| SCHEMBL17996498 | 0.78 | TSHR (0.47) | CYP2C9TSHRCYP2D6LMNAMAPT | |
| SCHEMBL14240823 | 0.77 | PPARG (0.41) | TSHRLTA4HPPARGPPARACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115594625-A | Method for preparing bazedoxifene | 济南明微医药科技有限公司（CN） | 2023-01-13 | — | — | CN | disclosed |
| WO-2008096129-A1 | NITROGEN CONTAINING HETROCYCLIC COMPOUNDS USEFUL AS BIFUNCTIONAL MODULATORS OF M3 RECEPTORS AND BETA- 2 RECEPTORS | ARGENTA DISCOVERY LTD (GB) | 2008-08-14 | — | — | WO | disclosed |
| WO-2008096129-A1 | NITROGEN CONTAINING HETROCYCLIC COMPOUNDS USEFUL AS BIFUNCTIONAL MODULATORS OF M3 RECEPTORS AND BETA- 2 RECEPTORS | ARGENTA DISCOVERY LTD (GB) | 2008-08-14 | — | — | WO | disclosed |