Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | PDIA6 | Q15084 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | STAT3 | P40763 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3690503 | 0.87 | SMN1; SMN2 (0.43) | SMN1; SMN2PDIA6MAPK1LMNAALOX15 | |
| SCHEMBL3365663 | 0.85 | NSD2 (0.37) | SMN1; SMN2MAPK1NPC1RAB9AMAPT | |
| SCHEMBL20521473 | 0.82 | KDM4E (0.33) | SMN1; SMN2MAPK1NPC1RAB9AMAPT | |
| SCHEMBL2474079 | 0.82 | KDM4E (0.49) | SMN1; SMN2LMNATSHRL3MBTL1KDM4E | |
| SCHEMBL1284438 | 0.79 | MAOB (0.45) | SMN1; SMN2LMNAMEN1KMT2ANPC1 | |
| SCHEMBL17669520 | 0.77 | NCF1 (0.48) | SMN1; SMN2PDIA6MAPK1LMNAALOX15 | |
| SCHEMBL22219023 | 0.76 | SMN1; SMN2 (0.48) | SMN1; SMN2PDIA6MAPK1LMNAALOX15 | |
| SCHEMBL7931164 | 0.76 | SMN1; SMN2 (0.44) | SMN1; SMN2PDIA6MAPK1LMNAALOX15 | |
| SCHEMBL21493100 | 0.75 | KMT2A (0.31) | SMN1; SMN2MEN1KMT2ARAB9AALDH1A1 | |
| SCHEMBL25405576 | 0.75 | PDIA6 (0.51) | SMN1; SMN2PDIA6MAPK1LMNAALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008075955-A2 | PROCESS FOR THE PREPARATION OF 1,4,5-TRISUBSTITUTED TRIAZOLES AND 3,4,5-TRISUBSTITUTED TRIAZOLES | STICHTING VOOR DE TECHNISCHE WETENSCHAPPEN (NL) | 2008-06-26 | — | — | WO | disclosed |