Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | NCOR1 | O75376 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4738996 | 0.78 | IGF1R (0.30) | — | |
| SCHEMBL4680634 | 0.64 | PSEN1 (0.33) | — | |
| SCHEMBL4679671 | 0.64 | MAPT (0.43) | — | |
| SCHEMBL4679789 | 0.61 | BLM (0.35) | — | |
| SCHEMBL4742817 | 0.61 | DPP4 (0.32) | HDAC3NCOR1HDAC1HDAC2HDAC8 | |
| SCHEMBL20163055 | 0.60 | NOTUM (0.54) | — | |
| SCHEMBL30037283 | 0.60 | NOTUM (0.54) | — | |
| SCHEMBL11046359 | 0.59 | CPB1 (0.39) | — | |
| SCHEMBL31434554 | 0.58 | NOTUM (0.56) | — | |
| SCHEMBL4680902 | 0.57 | MAPKAPK2 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1437349-B9 | SUBSTITUTED ISOXAZOLES AND THE USE THEREOF AS ANTIBIOTICS | S A L V A T LAB SA (ES) | 2008-09-10 | — | — | EP | disclosed |
| EP-1437349-B1 | SUBSTITUTED ISOXAZOLES AND THE USE THEREOF AS ANTIBIOTICS | S A L V A T LAB SA (ES) | 2007-08-15 | — | — | EP | disclosed |