Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | GPR88 | Q9GZN0 | 2/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | GRM7 | Q14831 | 2/20 | 0.39 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.38 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4242006 | 0.78 | HDAC3 (0.54) | — | |
| SCHEMBL13059171 | 0.73 | PTGS2 (0.59) | PTGS2CTSSCTSKERCC1ERCC4 | |
| SCHEMBL4245847 | 0.68 | USP30 (0.67) | — | |
| SCHEMBL4188307 | 0.68 | CNR1 (0.46) | — | |
| SCHEMBL19280966 | 0.67 | CYP2D6 (0.39) | — | |
| SCHEMBL20660478 | 0.67 | CYP2D6 (0.39) | — | |
| SCHEMBL4182300 | 0.67 | CYP2D6 (0.39) | — | |
| SCHEMBL20660476 | 0.67 | CYP2D6 (0.39) | — | |
| SCHEMBL19280968 | 0.67 | CYP2D6 (0.39) | — | |
| SCHEMBL30500841 | 0.67 | ALDH1A1 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1904446-A2 | AZABICYCLO DERIVATIVES AS MUSCARINIC RECEPTOR ANTAGONISTS | Ranbaxy Laboratories Limited (IN) | 2008-04-02 | — | — | EP | disclosed |
| WO-2007007282-A2 | AZABICYCLO DERIVATIVES AS MUSCARINIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2007-01-18 | — | — | WO | disclosed |