Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | FASN | P49327 | 13/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4179233 | 0.90 | GAA (0.56) | GAAALDH1A1SMN1; SMN2HSP90AA1L3MBTL1 | |
| SCHEMBL4180444 | 0.88 | GAA (0.60) | CA12CA1CA2CA7CA9 | |
| SCHEMBL4183554 | 0.87 | FASN (0.49) | FASNKDM1A | |
| SCHEMBL4199044 | 0.84 | CA12 (0.61) | CA12CA1CA2CA7CA9 | |
| SCHEMBL14162053 | 0.76 | KDM4E (0.52) | CA12CA1CA2CA7CA9 | |
| SCHEMBL14161742 | 0.75 | OPRM1 (0.42) | FASNKDM1A | |
| SCHEMBL4198155 | 0.69 | FASN (0.65) | FASN | |
| SCHEMBL30010047 | 0.68 | FASN (0.64) | FASN | |
| SCHEMBL4168210 | 0.68 | FASN (0.64) | FASN | |
| SCHEMBL29601441 | 0.68 | GAA (0.72) | GAAALDH1A1SMN1; SMN2HSP90AA1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008075064-A1 | PIPERIDINE DERIVATIVES FOR THE TREATMENT OF OBESITY | ASTRAZENECA AB (SE) | 2008-06-26 | — | — | WO | disclosed |