Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.62 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | CES2 | O00748 | 1/20 | 0.51 |
| ▸ | CES1 | P23141 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.48 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4764941 | 0.89 | ALDH1A1 (0.72) | GAAALDH1A1SMN1; SMN2L3MBTL1HSP90AA1 | |
| Tert-Butyl Formate SCHEMBL27622143 | 0.89 | GAA (0.58) | GAAALDH1A1SMN1; SMN2L3MBTL1HSP90AA1 | |
| SCHEMBL10126443 | 0.86 | GAA (0.76) | GAAALDH1A1SMN1; SMN2L3MBTL1HSP90AA1 | |
| SCHEMBL22767195 | 0.84 | GAA (1.00) | GAAALDH1A1SMN1; SMN2L3MBTL1HSP90AA1 | |
| SCHEMBL2378269 | 0.82 | GAA (0.69) | GAAALDH1A1SMN1; SMN2L3MBTL1HSP90AA1 | |
| SCHEMBL12311741 | 0.81 | HPGD (0.65) | ALDH1A1SMN1; SMN2HTTTSHRPOLB | |
| SCHEMBL15209063 | 0.81 | GAA (0.48) | GAAALDH1A1SMN1; SMN2L3MBTL1HSP90AA1 | |
| SCHEMBL11299599 | 0.81 | PKM (0.52) | GAAALDH1A1SMN1; SMN2L3MBTL1HSP90AA1 | |
| Hydrochloric Acid SCHEMBL29753302 | 0.80 | PKM (0.51) | GAAALDH1A1SMN1; SMN2L3MBTL1HSP90AA1 | |
| Hydrochloric Acid SCHEMBL15209798 | 0.80 | GAA (0.47) | GAAALDH1A1SMN1; SMN2L3MBTL1HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11357780-B2 | Methods and compositions relating to the inhibition of IP6K1 | THE CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2022-06-14 | — | — | US | disclosed |