Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 12/20 | 0.45 |
| ▸ | OGFOD1 | Q8N543 | 1/20 | 0.40 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.40 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.40 |
| ▸ | HIF1AN | Q9NWT6 | 1/20 | 0.40 |
| ▸ | APLNR | P35414 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | DRD5 | P21918 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4740765 | 0.91 | EGLN1 (0.42) | EGLN1OGFOD1EGLN2EGLN3HIF1AN | |
| SCHEMBL4739144 | 0.87 | EGLN1 (0.45) | EGLN1OGFOD1EGLN2EGLN3HIF1AN | |
| SCHEMBL4737006 | 0.85 | EGLN1 (0.52) | EGLN1OGFOD1EGLN2EGLN3HIF1AN | |
| SCHEMBL4985569 | 0.84 | EGLN1 (0.44) | EGLN1OGFOD1EGLN2EGLN3HIF1AN | |
| SCHEMBL4992285 | 0.84 | EGLN1 (0.54) | EGLN1OGFOD1EGLN2EGLN3HIF1AN | |
| SCHEMBL4738462 | 0.84 | EGLN3 (0.49) | EGLN1OGFOD1EGLN2EGLN3HIF1AN | |
| SCHEMBL14123846 | 0.83 | EGLN1 (0.44) | EGLN1OGFOD1EGLN2EGLN3HIF1AN | |
| SCHEMBL4740759 | 0.80 | EGLN1 (0.43) | EGLN1OGFOD1EGLN2EGLN3HIF1AN | |
| SCHEMBL4995811 | 0.80 | HIF1A (0.47) | EGLN1OGFOD1EGLN2EGLN3HIF1AN | |
| SCHEMBL4992269 | 0.80 | EGLN1 (0.45) | EGLN1OGFOD1EGLN2EGLN3HIF1AN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008089051-A1 | N-SUBSTITUTED GLYCINE DERIVATIVES: PROLYL HYDROXYLASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2008-07-24 | — | — | WO | claimed |