Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 10/20 | 0.42 |
| ▸ | APLNR | P35414 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | BTK | Q06187 | 1/20 | 0.38 |
| ▸ | EGLN3 | Q9H6Z9 | 2/20 | 0.38 |
| ▸ | OGFOD1 | Q8N543 | 1/20 | 0.38 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.38 |
| ▸ | HIF1AN | Q9NWT6 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TOP2A | P11388 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4739146 | 0.91 | EGLN1 (0.45) | EGLN1APLNREGLN3OGFOD1EGLN2 | |
| SCHEMBL4740759 | 0.88 | EGLN1 (0.43) | EGLN1APLNREGLN3OGFOD1EGLN2 | |
| SCHEMBL4995811 | 0.88 | HIF1A (0.47) | EGLN1APLNREGLN3OGFOD1EGLN2 | |
| SCHEMBL4737006 | 0.85 | EGLN1 (0.52) | EGLN1APLNREGLN3OGFOD1EGLN2 | |
| SCHEMBL4992314 | 0.84 | EGLN1 (0.44) | EGLN1APLNREGLN3OGFOD1EGLN2 | |
| SCHEMBL4991812 | 0.84 | EGLN1 (0.44) | EGLN1APLNREGLN3OGFOD1EGLN2 | |
| SCHEMBL4739144 | 0.79 | EGLN1 (0.45) | EGLN1APLNREGLN3OGFOD1EGLN2 | |
| SCHEMBL4992269 | 0.79 | EGLN1 (0.45) | EGLN1APLNREGLN3OGFOD1EGLN2 | |
| SCHEMBL4993614 | 0.79 | EGLN1 (0.44) | EGLN1APLNREGLN3OGFOD1EGLN2 | |
| SCHEMBL4992285 | 0.79 | EGLN1 (0.54) | EGLN1APLNREGLN3OGFOD1EGLN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008089051-A1 | N-SUBSTITUTED GLYCINE DERIVATIVES: PROLYL HYDROXYLASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2008-07-24 | — | — | WO | claimed |