Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 17/20 | 0.63 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.52 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.52 |
| ▸ | DRD2 | P14416 | 1/20 | 0.52 |
| ▸ | PDE4A | P27815 | 1/20 | 0.52 |
| ▸ | DRD3 | P35462 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7839165 | 0.88 | ABCB11 (0.64) | ADRB2ADRB1ABCB11DRD2PDE4A | |
| Hydrochloric Acid SCHEMBL7838052 | 0.87 | ABCB11 (0.63) | ADRB2ADRB1ABCB11DRD2PDE4A | |
| SCHEMBL8528251 | 0.84 | ABCB11 (0.73) | ADRB2ADRB1ABCB11DRD2PDE4A | |
| Hydrochloric Acid SCHEMBL8531813 | 0.84 | ABCB11 (0.72) | ADRB2ADRB1ABCB11DRD2PDE4A | |
| SCHEMBL9522342 | 0.81 | ADRB2 (0.72) | ADRB2ADRB1ABCB11DRD2PDE4A | |
| Hydrochloric Acid SCHEMBL8882013 | 0.80 | ADRB2 (0.71) | ADRB2ADRB1ABCB11DRD2PDE4A | |
| SCHEMBL8879323 | 0.80 | ADRB2 (0.61) | ADRB2ADRB1ABCB11DRD2PDE4A | |
| SCHEMBL9254881 | 0.80 | ABCB11 (0.55) | ADRB2ADRB1ABCB11DRD2PDE4A | |
| SCHEMBL7841548 | 0.79 | ADRB2 (0.61) | ADRB2ADRB1ABCB11DRD2PDE4A | |
| SCHEMBL9522645 | 0.79 | ABCB11 (0.53) | ADRB2ADRB1ABCB11DRD2PDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008096129-A1 | NITROGEN CONTAINING HETROCYCLIC COMPOUNDS USEFUL AS BIFUNCTIONAL MODULATORS OF M3 RECEPTORS AND BETA- 2 RECEPTORS | ARGENTA DISCOVERY LTD (GB) | 2008-08-14 | — | — | WO | disclosed |