SCHEMBL4739376

SCHEMBL4739376

CCO/C(Oc1ccccc1)=C(/C)C(=O)O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.49
HPGD P15428 3/20 0.43
TSHR P16473 2/20 0.43
RAB9A P51151 2/20 0.43
NPC1 O15118 2/20 0.43
CRHBP P24387 1/20 0.43
CRHR2 Q13324 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
PIN1 Q13526 2/20 0.42
MEN1 O00255 3/20 0.41
KMT2A Q03164 3/20 0.41
ALDH1A1 P00352 2/20 0.41
KDM4E B2RXH2 1/20 0.41
HSP90AA1 P07900 1/20 0.41
CYP1A2 P05177 1/20 0.41
CYP2D6 P10635 1/20 0.41
CYP2C9 P11712 1/20 0.41
ALOX15 P16050 1/20 0.41
MAPK1 P28482 1/20 0.41
CYP2C19 P33261 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2956113 0.85 ELANE (0.47) MAPTHPGDTDP1ALDH1A1KDM4E
SCHEMBL9487571 0.84 MAPT (0.50) MAPTHPGDTSHRRAB9ANPC1
SCHEMBL124445 0.81 MAPT (0.48) MAPTHPGDTSHRRAB9ANPC1
SCHEMBL10585445 0.79 MAPT (0.49) MAPTHPGDTSHRRAB9ANPC1
SCHEMBL1240435 0.79 ALDH1A1 (0.39) MAPTMEN1KMT2AALDH1A1KDM4E
SCHEMBL6786515 0.77 ALDH1A1 (0.50) MAPTTSHRALDH1A1KDM4ECYP2D6
Acetic Acid Phenyl Ester SCHEMBL1865089 0.77 ELANE (0.56) MAPTHPGDTSHRRAB9ANPC1
SCHEMBL18812995 0.76 MAPT (0.49) MAPTHPGDTSHRRAB9ANPC1
SCHEMBL37520 0.76 MAPT (0.56) MAPTHPGDTSHRRAB9ANPC1
SCHEMBL10892655 0.75 MAPT (0.43) MAPTHPGDTSHRRAB9ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008079519-A1 PHOTOSENSITIVE COMPOSITION WITH LOW YELLOWING UNDER UV-LIGHT AND SUNLIGHT EXPOSURE CLAST TRADING LIMITED (CN) 2008-07-03 WO claimed
US-20070099119-A1 Photosensitive composition with low yellowing under UV-light and sunlight exposure CHEMENCE, INC. 2007-05-03 US claimed