SCHEMBL9487571

SCHEMBL9487571

CCOC(Oc1ccccc1)=C(OCC)C(=O)O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.50
TSHR P16473 2/20 0.44
RAB9A P51151 3/20 0.44
NPC1 O15118 3/20 0.44
HPGD P15428 2/20 0.44
CRHBP P24387 1/20 0.44
CRHR2 Q13324 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
PIN1 Q13526 2/20 0.44
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
CYP1A2 P05177 1/20 0.42
CYP2D6 P10635 1/20 0.42
CYP2C9 P11712 1/20 0.42
ALOX15 P16050 1/20 0.42
MAPK1 P28482 1/20 0.42
CYP2C19 P33261 1/20 0.42
CASP3 P42574 1/20 0.42
SENP8 Q96LD8 1/20 0.42
HSD17B10 Q99714 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10585445 0.88 MAPT (0.49) MAPTTSHRRAB9ANPC1HPGD
SCHEMBL9487594 0.85 LMNA (0.49) MAPTHPGDTDP1MEN1KMT2A
SCHEMBL4739376 0.84 MAPT (0.49) MAPTTSHRRAB9ANPC1HPGD
SCHEMBL18812995 0.84 MAPT (0.49) MAPTTSHRRAB9ANPC1HPGD
SCHEMBL124445 0.83 MAPT (0.48) MAPTTSHRRAB9ANPC1HPGD
SCHEMBL124444 0.79 MAPT (0.48) MAPTTSHRRAB9ANPC1HPGD
SCHEMBL738068 0.78 ALDH1A1 (0.46) MAPTTSHRCYP2D6ALOX15HSD17B10
SCHEMBL37520 0.77 MAPT (0.56) MAPTTSHRRAB9ANPC1HPGD
SCHEMBL10892655 0.77 MAPT (0.43) MAPTTSHRRAB9ANPC1HPGD
SCHEMBL18422860 0.76 MAPT (0.42) MAPTTSHRRAB9ANPC1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0321618-B1 PHOTOSENSITIVE HARDENABLE COMPOSITIONS DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1993-02-17 EP disclosed
EP-0361409-A2 Flame-retardant liquid photosensitive resin composition MITSUBISHI RAYON CO., LTD. (JP) 1990-04-04 EP disclosed
US-4885229-A CONTAINING ACRYLATED ESTERS 501 DAICEL CHEMICAL INDUSTRIES LTD. (JP) 1989-12-05 US disclosed
EP-0321618-A1 Photosensitive hardenable compositions DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1989-06-28 EP disclosed