Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | CRHBP | P24387 | 1/20 | 0.48 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.48 |
| ▸ | PPARA | Q07869 | 11/20 | 0.47 |
| ▸ | PPARD | Q03181 | 5/20 | 0.47 |
| ▸ | PPARG | P37231 | 5/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4740491 | 0.88 | ALDH1A1 (0.60) | ALDH1A1NPC1GAAMAPTMEN1 | |
| SCHEMBL4739681 | 0.88 | MAPT (0.61) | ALDH1A1NPC1GAAMAPTMEN1 | |
| SCHEMBL4738839 | 0.88 | NPC1 (0.57) | ALDH1A1NPC1GAAMAPTMEN1 | |
| SCHEMBL4740775 | 0.87 | MAPT (0.44) | ALDH1A1NPC1GAAMAPTMEN1 | |
| SCHEMBL4738093 | 0.87 | NPC1 (0.56) | ALDH1A1NPC1GAAMAPTMEN1 | |
| SCHEMBL4738817 | 0.86 | ALDH1A1 (0.55) | ALDH1A1NPC1GAAMAPTMEN1 | |
| SCHEMBL4738885 | 0.85 | MAPT (0.49) | ALDH1A1NPC1GAAMAPTMEN1 | |
| SCHEMBL4741834 | 0.84 | ALDH1A1 (0.55) | ALDH1A1NPC1GAAMAPTMEN1 | |
| SCHEMBL4741580 | 0.83 | PPARA (0.56) | ALDH1A1NPC1GAAPPARAPPARD | |
| SCHEMBL4739607 | 0.82 | PPARD (0.44) | ALDH1A1NPC1GAAMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008087367-A2 | SUBSTITUTED (PHENYLTHIAZOLYL)-PHENYL-PROPAN-1-ONE AND (PHENYLOXAZODYL)-PHENYL-PROPAN-1-ONE DERIVATIVES, PREPARATIONS AND USES OF SAME | GENFIT (FR) | 2008-07-24 | — | — | WO | disclosed |
| WO-2008087367-A2 | SUBSTITUTED (PHENYLTHIAZOLYL)-PHENYL-PROPAN-1-ONE AND (PHENYLOXAZODYL)-PHENYL-PROPAN-1-ONE DERIVATIVES, PREPARATIONS AND USES OF SAME | GENFIT (FR) | 2008-07-24 | — | — | WO | disclosed |