SCHEMBL4739675

SCHEMBL4739675

CCOC(=O)C(=O)c1ccc(Oc2ccccc2)cc1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.57
MAPT P10636 2/20 0.57
NPC1 O15118 2/20 0.56
RAB9A P51151 2/20 0.56
HPGD P15428 1/20 0.56
CRHBP P24387 1/20 0.56
CRHR2 Q13324 1/20 0.56
PARP10 Q53GL7 1/20 0.51
SRD5A2 P31213 3/20 0.50
SMN1; SMN2 Q16637 3/20 0.50
LTA4H P09960 1/20 0.50
HTT P42858 1/20 0.49
LMNA P02545 1/20 0.49
THRB P10828 1/20 0.49
ERCC5 P28715 1/20 0.49
FEN1 P39748 1/20 0.49
MAPK14 Q16539 1/20 0.48
HDAC3 O15379 1/20 0.48
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20326025 0.88 MMP13 (0.53) ALDH1A1MAPTNPC1RAB9AHPGD
SCHEMBL4783812 0.86 AKR1C3 (0.58) ALDH1A1MAPTNPC1RAB9AHPGD
SCHEMBL97859 0.86 ALDH1A1 (0.73) ALDH1A1MAPTNPC1SMN1; SMN2LMNA
SCHEMBL20325605 0.85 SMN1; SMN2 (0.49) ALDH1A1MAPTHPGDSMN1; SMN2CES2
SCHEMBL16613214 0.85 NPC1 (0.49) ALDH1A1MAPTNPC1RAB9AHPGD
SCHEMBL9402612 0.84 TP53 (0.55) ALDH1A1MAPTRAB9AHTTLMNA
Water SCHEMBL27483870 0.84 ALDH1A1 (0.71) ALDH1A1MAPTNPC1SMN1; SMN2LMNA
SCHEMBL6340266 0.84 ALDH1A1 (0.54) ALDH1A1MAPTNPC1RAB9AHPGD
SCHEMBL1172378 0.83 MAPT (0.60) ALDH1A1MAPTRAB9AHPGDSMN1; SMN2
SCHEMBL1730420 0.83 SMN1; SMN2 (0.66) ALDH1A1MAPTNPC1RAB9AHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070099119-A1 Photosensitive composition with low yellowing under UV-light and sunlight exposure CHEMENCE, INC. 2007-05-03 US claimed
US-4038164-A PHOTOPOLYMERIZABLE ARYL AND HETEROCYCLIC GLYOXYLATE COMPOSITIONS AND PROCESS STAUFFER CHEMICAL COMPANY (US) 1977-07-26 US claimed
EP-3680234-B1 SULFONIUM SALT PHOTOINITIATOR, PREPARATION METHOD THEREFOR, PHOTOCURABLE COMPOSITION CONTAINING SULFONIUM SALT PHOTOINITIATOR, AND USE THEREOF CHANGZHOU TRONLY NEW ELECTRONIC MAT CO LTD (CN) 2022-01-12 EP disclosed
EP-3680234-A1 SULFONIUM SALT PHOTOINITIATOR, PREPARATION METHOD THEREFOR, PHOTOCURABLE COMPOSITION CONTAINING SULFONIUM SALT PHOTOINITIATOR, AND USE THEREOF Changzhou Tronly New Electronic Materials Co., Ltd (CN) 2020-07-15 EP disclosed
WO-2020015966-A1 PHOTO-CURABLE RESIN COMPOSITION FOR 3D PRINTING CLARIANT INTERNATIONAL LTD (CH) 2020-01-23 WO disclosed
WO-2020015964-A1 PHOTO-CURABLE RESIN COMPOSITION FOR 3D PRINTING CLARIANT INTERNATIONAL LTD (CH) 2020-01-23 WO disclosed
US-20190322676-A1 CERAMIDE GALACTOSYLTRANSFERASE INHIBITORS FOR THE TREATMENT OF DISEASE BIOMARIN PHARM INC (US) 2019-10-24 US disclosed
US-9150723-B2 Curable resin composition THREE BOND FINE CHEMICAL CO., LTD. (JP) 2015-10-06 US disclosed
US-20140329926-A1 CURABLE RESIN COMPOSITION THREE BOND FINE CHEMICAL CO., LTD (JP) 2014-11-06 US disclosed
EP-2792694-A1 CURABLE RESIN COMPOSITION Three Bond Fine Chemical Co., Ltd. (JP) 2014-10-22 EP disclosed
CN-102803205-A Base and radical generator, composition using same and method for curing same THREE BOND CO LTD 2012-11-28 CN disclosed
CN-1300285-A Hydroxyiminoalkanoic Acid Derivatives TAKEDA CHEMICAL INDUSTRIES LTD (JP) 2001-06-20 CN disclosed
WO-2001019939-A1 FLUORESCENT MALEIMIDES AND USES THEREOF CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2001-03-22 WO disclosed
EP-1077957-A1 OXYIMINOALKANOIC ACID DERIVATIVES WITH HYPOGLYCEMIC AND HYPOLIPIDEMIC ACTIVITY Takeda Chemical Industries, Ltd. (JP) 2001-02-28 EP disclosed
WO-1999058510-A1 OXYIMINOALKANOIC ACID DERIVATIVES WITH HYPOGLYCEMIC AND HYPOLIPIDEMIC ACTIVITY TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1999-11-18 WO disclosed
EP-0253370-B1 1,3,5-Trithian derivatives NIHON NOHYAKU CO LTD (JP) 1993-11-18 EP disclosed
US-4816475-A ANTIARTERIOSCLEROTIC OR ANTIHYPERLIPEMIC AGENTS NIHON NOHYAKU CO. LTD. (JP) 1989-03-28 US disclosed
EP-0253370-A1 1,3,5-Trithian derivatives NIHON NOHYAKU CO., LTD. (JP) 1988-01-20 EP disclosed
US-4279720-A PHENYLGLYOXYLATE PHOTOINITIATOR WITH POLYALKYLPIPERIDINE STABILIZER CIBA-GEIGY CORPORATION (US) 1981-07-21 US disclosed
US-4229274-A PHOTOINITIATOR, PHOTOSENSITIZER, QUENCHER, AND COMPOUNDS CONTAINING ACRYLYLOXY GROUPS PPG INDUSTRIES, INC. (US) 1980-10-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190322676-A1 CERAMIDE GALACTOSYLTRANSFERASE INHIBITORS FOR THE TREATMENT OF DISEASE UGCG, MAN2B1, GBA1 ALDH1A1 2406/4885MAPT 308/4885NPC1 83/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.