SCHEMBL4739711

SCHEMBL4739711

C1CCC(PC2CCCCC2)CC1.CC(C)c1ccccc1-c1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.42
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
CA9 Q16790 1/20 0.42
ALDH1A1 P00352 3/20 0.37
CYP3A4 P08684 1/20 0.37
CYP2D6 P10635 1/20 0.37
CYP2C9 P11712 1/20 0.37
CYP2C19 P33261 1/20 0.37
FFAR2 O15552 1/20 0.37
PPARA Q07869 2/20 0.36
PPARG P37231 1/20 0.36
LMNA P02545 2/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
USP1 O94782 3/20 0.36
WDR48 Q8TAF3 3/20 0.36
TRPA1 O75762 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29169833 0.90 PTPN1 (0.37) CA12CA1CA2CA9ALDH1A1
SCHEMBL1485527 0.84 ROCK2 (0.41) CYP2C9CYP2C19LMNAMEN1KMT2A
SCHEMBL28003862 0.83 CA12 (0.43) CA12CA1CA2CA9ALDH1A1
SCHEMBL28445756 0.80 ROCK2 (0.37) ALDH1A1LMNASMN1; SMN2NPSR1ROCK2
Benzene SCHEMBL28765069 0.79 CA1 (0.58) CA12CA1CA2CA9ALDH1A1
SCHEMBL146177 0.79 CA1 (0.58) CA12CA1CA2CA9ALDH1A1
SCHEMBL29613123 0.79 CA1 (0.58) CA12CA1CA2CA9ALDH1A1
SCHEMBL29033296 0.79 HDAC1 (0.39) CA12CA1CA2CA9ALDH1A1
SCHEMBL25202551 0.78 ROCK2 (0.55) LMNAMEN1KMT2ANPSR1ROCK2
Hydrochloric Acid SCHEMBL28861669 0.77 CA1 (0.56) CA12CA1CA2CA9ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110408010-A A kind of D-A type conjugated polymer of the lactone containing condensed ring and the preparation method and application thereof NAT CT NANOSCIENCE & TECHNOLOGY CHINA 2019-11-05 CN claimed
CN-107987849-A A kind of liquid crystal aligning immunomodulator compounds and preparation method thereof 烟台丰鲁精细化工有限责任公司 2018-05-04 CN claimed
CN-105585566-B A kind of synthetic method of indone and Imidazopyridine compound 河南师范大学 2017-12-29 CN claimed
CN-104926818-B A kind of synthetic method of pyrazolo [5,1 a] isoindoles compound 河南师范大学 2017-10-20 CN claimed
CN-105801582-A Novel dihydro pteridinone derivative, preparing method thereof and application to medicine 合肥工业大学 2016-07-27 CN claimed
CN-105801578-A Synthetic method and application of half-saturation pyrazine derivative 华南理工大学 2016-07-27 CN claimed
CN-105622625-A Synthesis method of benzopyrone and imidazopyridine compound UNIV HENAN NORMAL 2016-06-01 CN claimed
CN-105585566-A Method for synthesizing indene ketone and imidazole and pyridine compounds UNIV HENAN NORMAL 2016-05-18 CN claimed
CN-104926818-A Method for synthesizing pyrazolo-[5, 1-alpha]isoindole compounds UNIV HENAN NORMAL 2015-09-23 CN claimed
WO-2023124205-A1 ORGANIC COMPOUNDS, ORGANIC ELECTROLUMINESCENT DEVICE AND ELECTRONIC APPARATUS 陕西莱特光电材料股份有限公司 2023-07-06 WO disclosed
WO-2023116888-A1 FIVE- AND SIX-MEMBERED COMPOUND, PREPARATION METHOD, PHARMACEUTICAL COMPOSITION AND USE 杭州多域生物技术有限公司 2023-06-29 WO disclosed
WO-2023098752-A1 NOVEL NON-FLUORINATED QUINOLONE COMPOUND AND APPLICATION THEREOF 广州白云山医药集团股份有限公司白云山制药总厂 2023-06-08 WO disclosed
WO-2023078411-A1 AZASPIRO COMPOUND 南京明德新药研发有限公司 2023-05-11 WO disclosed
WO-2020192581-A1 WEE1 INHIBITOR AND PREPARATION AND USE THEREOF 首药控股(北京)有限公司 2020-10-01 WO disclosed
CN-104059039-A Fused ring compound with GPR40 receptor function adjusting effect CHIA TAI TIANQING PHARMACEUTICAL GROUP CO LTD 2014-09-24 CN disclosed
CN-102470158-A Processes for preparing protease inhibitors of hepatitis c virus MERCK SHARP & DOHME 2012-05-23 CN disclosed
CN-102239152-A Novel amide derivative and use thereof as medicine MITSUBISHI TANABE PHARMA CORP 2011-11-09 CN disclosed
EP-1581467-A4 LIGANDS FOR METALS AND IMPROVED METAL-CATALYZED PROCESSES BASED THEREON MASSACHUSETTS INST TECHNOLOGY (US) 2008-08-13 EP disclosed
EP-1581467-A2 LIGANDS FOR METALS AND IMPROVED METAL-CATALYZED PROCESSES BASED THEREON MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2005-10-05 EP disclosed
WO-2004052939-A2 LIGANDS FOR METALS AND IMPROVED METAL-CATALYZED PROCESSES BASED THEREON MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2004-06-24 WO disclosed