SCHEMBL29033296

SCHEMBL29033296

C1CCC(PC2CCCCC2)CC1.Cc1ccccc1-c1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC1 Q13547 1/20 0.39
HDAC2 Q92769 1/20 0.39
S1PR1 P21453 1/20 0.39
S1PR5 Q9H228 1/20 0.39
ALDH1A1 P00352 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
ENPP3 O14638 1/20 0.39
ENPP1 P22413 1/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
LMNA P02545 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
NPC1 O15118 1/20 0.38
HPGD P15428 1/20 0.38
TSHR P16473 1/20 0.38
RAB9A P51151 1/20 0.38
CA12 O43570 1/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
CA9 Q16790 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biphenyl SCHEMBL1207219 0.81 ALDH1A1 (0.43) ALDH1A1SMN1; SMN2MEN1KMT2ALMNA
Biphenyl SCHEMBL28655421 0.81 ALDH1A1 (0.43) ALDH1A1SMN1; SMN2MEN1KMT2ALMNA
SCHEMBL25302717 0.80 FFAR2 (0.44) S1PR1ALDH1A1SMN1; SMN2LMNANPC1
SCHEMBL3238242 0.79 NPSR1 (0.36) ALDH1A1SMN1; SMN2MEN1KMT2ALMNA
SCHEMBL4739711 0.79 CA12 (0.42) ALDH1A1SMN1; SMN2MEN1KMT2ALMNA
Biphenyl SCHEMBL19181492 0.77 ALDH1A1 (0.39) ALDH1A1SMN1; SMN2MEN1KMT2ALMNA
SCHEMBL616 0.77 ESR2 (0.54) ALDH1A1SMN1; SMN2ENPP3ENPP1NPC1
SCHEMBL29706107 0.77 ESR2 (0.54) ALDH1A1SMN1; SMN2ENPP3ENPP1NPC1
SCHEMBL28793120 0.76 ENPP3 (0.44) ALDH1A1SMN1; SMN2ENPP3ENPP1NPC1
Biphenyl SCHEMBL19181494 0.76 ALDH1A1 (0.38) ALDH1A1MEN1KMT2ALMNARAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116410215-A Aryl boric acid containing organic carbon free radical, derivative and preparation method thereof 西安交通大学 2023-07-11 CN claimed
CN-116410215-A Aryl boric acid containing organic carbon free radical, derivative and preparation method thereof 西安交通大学 2023-07-11 CN disclosed