Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 3/20 | 0.41 |
| ▸ | CDK5 | Q00535 | 3/20 | 0.41 |
| ▸ | CDK5R1 | Q15078 | 3/20 | 0.41 |
| ▸ | CCNB2 | O95067 | 2/20 | 0.41 |
| ▸ | CDK1 | P06493 | 2/20 | 0.41 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3348614 | 0.72 | MEN1 (0.45) | MEN1KMT2AHSD17B10KDM4EHPGD | |
| SCHEMBL3055898 | 0.70 | KDM4E (0.45) | MEN1KMT2AHSD17B10KDM4EHPGD | |
| SCHEMBL678673 | 0.69 | HTR2C (0.54) | MEN1KMT2AHSD17B10KDM4EHPGD | |
| SCHEMBL14355018 | 0.67 | KDM4E (0.57) | MEN1KMT2AHSD17B10KDM4EHPGD | |
| SCHEMBL296017 | 0.65 | HSD17B10 (0.48) | MEN1KMT2AHSD17B10KDM4EHPGD | |
| SCHEMBL30569666 | 0.64 | HTR2A (0.57) | MEN1KMT2AHSD17B10KDM4ECYP1A2 | |
| SCHEMBL1120971 | 0.64 | HTR2A (0.57) | MEN1KMT2AHSD17B10KDM4ECYP1A2 | |
| SCHEMBL30569664 | 0.64 | HTR2A (0.57) | MEN1KMT2AHSD17B10KDM4ECYP1A2 | |
| SCHEMBL10019851 | 0.64 | HTR2A (0.57) | MEN1KMT2AHSD17B10KDM4ECYP1A2 | |
| SCHEMBL6529801 | 0.62 | HTR2A (0.54) | MEN1KMT2AHSD17B10KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008125658-A1 | 4,5,11,11A-TETRAHYDRO-1H,6H-OXAZOLO[3',4':1,6]PYRIDO[3,4-B]INDOL-3-ONE DERIVATIVES AND THERAPEUTIC USE THEREOF | FOURTILLAN (FR) | 2008-10-23 | — | — | WO | disclosed |
| WO-2008101824-A1 | IMIDAZO[1',5':1,6] PYRIDO[3,4-B]INDOLES DERIVATIVES AND THERAPEUTICAL USE THEREOF | FOURTILLAN (FR) | 2008-08-28 | — | — | WO | disclosed |