SCHEMBL3348614

SCHEMBL3348614

O=C1C=Cc2[nH]c3ccccc3c2C1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.45
KMT2A Q03164 4/20 0.45
HSD17B10 Q99714 3/20 0.45
KDM4E B2RXH2 6/20 0.44
ALDH1A1 P00352 5/20 0.44
HPGD P15428 2/20 0.44
HTT P42858 2/20 0.44
LMNA P02545 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
GLA P06280 1/20 0.44
GAA P10253 1/20 0.44
ATM Q13315 1/20 0.44
CYP1A2 P05177 2/20 0.44
CYP2C19 P33261 1/20 0.44
CCNT1 O60563 1/20 0.43
CCNB2 O95067 1/20 0.43
CDK1 P06493 1/20 0.43
CCNB1 P14635 1/20 0.43
CCNA2 P20248 1/20 0.43
CDK2 P24941 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11443146 0.73 CA1 (0.45) MEN1KMT2AHSD17B10ALDH1A1CCNT1
SCHEMBL4739727 0.72 MEN1 (0.42) MEN1KMT2AHSD17B10KDM4EALDH1A1
SCHEMBL5891207 0.72 HSD17B10 (0.44) MEN1KMT2AHSD17B10KDM4EALDH1A1
SCHEMBL7078918 0.71 KDM4E (0.44) MEN1KMT2AHSD17B10KDM4EALDH1A1
SCHEMBL14355018 0.69 KDM4E (0.57) MEN1KMT2AHSD17B10KDM4EALDH1A1
SCHEMBL2307927 0.69 HTR2A (0.43) MEN1KMT2AHSD17B10KDM4EALDH1A1
SCHEMBL4127395 0.69 KDM4E (0.42) MEN1KMT2AHSD17B10KDM4EALDH1A1
SCHEMBL23121575 0.69 MEN1 (0.42) MEN1KMT2AHSD17B10KDM4EALDH1A1
SCHEMBL10759873 0.68 CDC25A (0.50) MEN1KMT2AHSD17B10KDM4EALDH1A1
SCHEMBL7079413 0.68 MEN1 (0.41) MEN1KMT2AHSD17B10KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007047579-A2 A NOVEL THERAPEUTIC TARGET FOR PROTOZOAL DISEASES VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) 2007-04-26 WO claimed
US-5801190-A Fused pyrrolo 2,3-C! carbazole-6-ones CEPHALON, INC. (US) 1998-09-01 US claimed
CN-117616032-A Rare earth complex 东曹株式会社 2024-02-27 CN disclosed
WO-2010042445-A1 CARBAZOLE COMPOUNDS AND THERAPEUTIC USES OF THE COMPOUNDS CLEVELAND BIOLABS, INC. (US) 2010-04-15 WO disclosed
US-6821644-B2 BIS(DIARYLAMINO)ARYLENE COMPOUND; BRILLIANCE, DURABILITY SAMSUNG SDI CO., LTD. (KR) 2004-11-23 US disclosed
CN-1098266-C Fused pyrrolo (2,3-C) carbazole-6-ones which potentiate activity of gamma interferon CEPHALON INC (US) 2003-01-08 CN disclosed
CN-1098266-C Fused pyrrolo (2,3-C) carbazole-6-ones which potentiate activity of gamma interferon CEPHALON INC (US) 2003-01-08 CN disclosed
EP-0885229-B1 FUSED PYRROLO(2,3-C)CARBAZOLE-6-ONES WHICH POTENTIATE ACTIVITY OF GAMMA INTERFERON CEPHALON INC (US) 2000-08-02 EP disclosed
CN-1211254-A Fused pyrrolo (2,3-C) carbazole-6-ones which potentiate activity of gamma interferon CEPHALON INC (US) 1999-03-17 CN disclosed
CN-1211254-A Fused pyrrolo (2,3-C) carbazole-6-ones which potentiate activity of gamma interferon CEPHALON INC (US) 1999-03-17 CN disclosed
EP-0885229-A1 FUSED PYRROLO(2,3-C)CARBAZOLE-6-ONES WHICH POTENTIATE ACTIVITY OF GAMMA INTERFERON CEPHALON, INC. (US) 1998-12-23 EP disclosed
US-5801190-A Fused pyrrolo 2,3-C! carbazole-6-ones CEPHALON, INC. (US) 1998-09-01 US disclosed
US-5801190-A Fused pyrrolo 2,3-C! carbazole-6-ones CEPHALON, INC. (US) 1998-09-01 US disclosed
US-5801190-A Fused pyrrolo 2,3-C! carbazole-6-ones CEPHALON, INC. (US) 1998-09-01 US disclosed
WO-1997031002-A9 FUSED PYRROLO(2,3-C)CARBAZOLE-6-ONES WHICH POTENTIATE ACTIVITY OF GAMMA INTERFERON 1997-10-30 WO disclosed
WO-1997031002-A1 FUSED PYRROLO(2,3-C)CARBAZOLE-6-ONES WHICH POTENTIATE ACTIVITY OF GAMMA INTERFERON CEPHALON, INC. (US) 1997-08-28 WO disclosed
US-5616724-A FOR POTENTIATION OF HUMAN INTERFERON-GAMMA; IMMUNOLOGY CEPHALON, INC. (US) 1997-04-01 US disclosed