Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRC | P08575 | 1/20 | 0.59 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.59 |
| ▸ | MRGPRX4 | Q96LA9 | 4/20 | 0.57 |
| ▸ | TP53 | P04637 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | RXRA | P19793 | 1/20 | 0.55 |
| ▸ | RXRB | P28702 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | XBP1 | P17861 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | PTPRG | P23470 | 1/20 | 0.55 |
| ▸ | MITF | O75030 | 1/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.55 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.55 |
| ▸ | RELA | Q04206 | 1/20 | 0.55 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7908609 | 0.85 | MRGPRX4 (0.61) | PTPRCPTPN1MRGPRX4NPC1RAB9A | |
| SCHEMBL1388182 | 0.83 | PTGER1 (0.60) | MRGPRX4TP53HPGDHTTRXRA | |
| SCHEMBL1388211 | 0.82 | PTGER1 (0.60) | MRGPRX4TP53HPGDRXRARXRB | |
| SCHEMBL5839878 | 0.82 | PTGER1 (0.56) | MRGPRX4TP53HPGDHTTRXRA | |
| SCHEMBL112903 | 0.81 | SGMS2 (0.66) | HTTNPC1KMT2APTGER1MAPT | |
| SCHEMBL29433417 | 0.81 | SGMS2 (0.66) | HTTNPC1KMT2APTGER1MAPT | |
| SCHEMBL1388149 | 0.81 | CAPN1 (0.60) | MRGPRX4HTTNPC1RAB9AMEN1 | |
| SCHEMBL10390231 | 0.80 | MAOB (0.52) | PTPRCPTPN1MRGPRX4TP53HPGD | |
| SCHEMBL27610143 | 0.80 | GAA (0.64) | HPGDHTTRXRARXRBNPC1 | |
| SCHEMBL28346227 | 0.79 | RXRA (0.56) | MRGPRX4HTTRXRARXRBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008090357-A2 | N, N; -SUBSTITUTED PIPERAZINES BINDING TO MELANOCORTIN RECEPTOR | PALATIN TECHNOLOGIES, INC. (US) | 2008-07-31 | — | — | WO | disclosed |
| US-6984645-B2 | Dual inhibitors of adipocyte fatty acid binding protein and keratinocyte fatty acid binding protein | BRISTOL-MYERS SQUIBB COMPANY (US) | 2006-01-10 | — | — | US | disclosed |