Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 2/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 7/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 7/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | DHFR | P00374 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3058971 | 0.84 | GRIN1 (0.35) | CNR1CNR2GRIN1GRIN2AMAPT | |
| SCHEMBL4733703 | 0.75 | HCAR3 (0.46) | MAPTALDH1A1GAA | |
| SCHEMBL7492564 | 0.75 | KDM4E (0.55) | CNR1MAPTKDM4ECYP1A2 | |
| SCHEMBL15652618 | 0.70 | KDM4E (0.48) | CNR1MAPTKDM4EALDH1A1GAA | |
| SCHEMBL3063808 | 0.68 | MEN1 (0.39) | GRIN1GRIN2AGRIA2CYP2C19SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL3063650 | 0.67 | MEN1 (0.38) | GRIN1GRIN2AGRIA2CYP2C19SMN1; SMN2 | |
| SCHEMBL4269638 | 0.65 | GBA1 (0.43) | CNR1MAPTKDM4EALDH1A1MAPK1 | |
| SCHEMBL4735282 | 0.65 | BCHE (0.46) | — | |
| Hydrochloric Acid SCHEMBL4739571 | 0.64 | BCHE (0.45) | — | |
| SCHEMBL9463877 | 0.64 | MAPT (0.51) | CNR1CNR2MAPTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008073461-A2 | ION CHANNEL MODULATORS | WYETH (US) | 2008-06-19 | — | — | WO | disclosed |