Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 2/20 | 0.46 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | RXRA | P19793 | 7/20 | 0.40 |
| ▸ | RXRB | P28702 | 1/20 | 0.40 |
| ▸ | RXRG | P48443 | 1/20 | 0.40 |
| ▸ | GBA1 | P04062 | 1/20 | 0.39 |
| ▸ | CXCR2 | P25025 | 4/20 | 0.38 |
| ▸ | CXCR1 | P25024 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3060027 | 0.84 | CACNA1H (0.39) | HCAR3CACNA1HKMT2ARXRAGBA1 | |
| SCHEMBL3823160 | 0.78 | HCAR3 (0.41) | HCAR3CACNA1HKMT2ARXRARXRB | |
| SCHEMBL3823885 | 0.78 | KCNQ3 (0.50) | KMT2AMEN1ALDH1A1LMNAMAPT | |
| SCHEMBL5430899 | 0.75 | HCAR3 (0.54) | HCAR3KMT2AGBA1MEN1ALDH1A1 | |
| SCHEMBL4736030 | 0.75 | CACNA1H (0.47) | CACNA1HKMT2AGBA1MEN1ALDH1A1 | |
| SCHEMBL4739784 | 0.75 | CNR1 (0.37) | ALDH1A1GAAMAPT | |
| SCHEMBL13611416 | 0.75 | HCAR3 (0.76) | HCAR3RXRARXRBRXRGGBA1 | |
| SCHEMBL3049317 | 0.74 | KMT2A (0.60) | KMT2ACXCR2CXCR1MEN1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL27869687 | 0.73 | HCAR3 (0.73) | HCAR3RXRARXRBRXRGGBA1 | |
| SCHEMBL14534877 | 0.73 | HCAR3 (0.58) | HCAR3KMT2ARXRARXRBRXRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008073461-A2 | ION CHANNEL MODULATORS | WYETH (US) | 2008-06-19 | — | — | WO | disclosed |