SCHEMBL4739813

SCHEMBL4739813

N#COC1=C(c2ccccc2)C(=O)NC1=O

nearest known ligand 0.46

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ GSK3B P49841 10/20 0.46
▸ PTGS2 P35354 5/20 0.45
▸ SLK Q9H2G2 1/20 0.39
▸ PDE4B Q07343 1/20 0.36
▸ SERPINE1 P05121 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL114611 0.76 PTGS2 (0.67) GSK3BPTGS2PDE4B
SCHEMBL211025 0.76 PDE4B (0.59) GSK3BPTGS2SLKPDE4BSERPINE1
SCHEMBL5434280 0.74 GSK3B (0.52) GSK3BPTGS2SLK
SCHEMBL11094753 0.74 GSK3B (0.49) GSK3BPTGS2SLK
SCHEMBL9474080 0.74 PTGS2 (0.64) GSK3BPTGS2
SCHEMBL9360541 0.71 PTGS2 (0.49) GSK3BPTGS2SLKPDE4B
SCHEMBL27825209 0.71 GSK3B (0.42) GSK3BPTGS2
SCHEMBL94149 0.71 GSK3B (0.58) GSK3BPTGS2PDE4B
SCHEMBL9333966 0.70 PTGS2 (0.47) GSK3BPTGS2
SCHEMBL27804436 0.69 GSK3B (0.47) GSK3BPTGS2SLKPDE4B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4010291-B1 PHARMACEUTICAL PACKAGES WITH COATINGS COMPRISING POLYCYANURATES CORNING INC (US) 2025-12-17 — — EP disclosed
US-20240016699-A1 PHARMACEUTICAL PACKAGES WITH COATINGS COMPRISING POLYCYANURATES CORNING INC (US) 2024-01-18 — — US disclosed
US-11707411-B2 Pharmaceutical packages with coatings comprising polycyanurates CORNING INCORPORATED (US) 2023-07-25 — — US disclosed
CN-115175857-A Pharmaceutical packaging with coating comprising polycyanurate 康宁股份有限公司 2022-10-11 — — CN disclosed
EP-4010291-A1 PHARMACEUTICAL PACKAGES WITH COATINGS COMPRISING POLYCYANURATES Corning Incorporated (US) 2022-06-15 — — EP disclosed
WO-2008082108-A1 ORGANIC COPOLYMER FOR PREPARING ORGANIC ANTIREFLECTIVE COATING, METHOD OF PREPARING THE SAME, AND COMPOSITION COMPRISING THE SAME HYOSUNG CORPORATION (KR) 2008-07-10 — — WO disclosed
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