⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL129086 | 1.00 | — | — | |
| SCHEMBL4740353 | 0.86 | LMNA (0.59) | — | |
| SCHEMBL4738613 | 0.86 | LMNA (0.59) | — | |
| SCHEMBL4787242 | 0.85 | LMNA (0.68) | — | |
| SCHEMBL4740162 | 0.85 | LMNA (0.68) | — | |
| SCHEMBL17866535 | 0.83 | — | — | |
| SCHEMBL9046627 | 0.83 | ALDH1A1 (0.52) | — | |
| SCHEMBL11147236 | 0.83 | LMNA (0.71) | — | |
| SCHEMBL9631208 | 0.83 | LMNA (0.71) | — | |
| SCHEMBL4433229 | 0.83 | LMNA (0.71) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8324273-B2 | Catechol protected levodopa diester prodrugs, compositions, and methods of use | XENOPORT, INC. (US) | 2012-12-04 | — | — | US | disclosed |
| US-20080171789-A1 | Catechol protected levodopa diester prodrugs, compositions, and methods of use | XENOPORT, INC. | 2008-07-17 | — | — | US | disclosed |
| WO-2008079387-A1 | CATECHOL PROTECTED LEVODOPA DIESTER PRODRUGS, COMPOSITIONS, AND METHODS OF USE | XENOPORT, INC. (US) | 2008-07-03 | — | — | WO | disclosed |