SCHEMBL474029

SCHEMBL474029

CCC(C)(C)c1ccc([O])c(C(C)(C)CC)c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 6/20 0.48
SMN1; SMN2 Q16637 5/20 0.48
NPSR1 Q6W5P4 5/20 0.48
MEN1 O00255 4/20 0.48
KMT2A Q03164 4/20 0.48
ALDH1A1 P00352 2/20 0.48
RAB9A P51151 4/20 0.47
NPC1 O15118 3/20 0.47
LMNA P02545 1/20 0.47
CASP3 P42574 1/20 0.47
ATM Q13315 1/20 0.47
SENP8 Q96LD8 1/20 0.47
SENP7 Q9BQF6 1/20 0.47
SENP6 Q9GZR1 1/20 0.47
MAPT P10636 5/20 0.40
HTT P42858 3/20 0.40
UBE2N P61088 2/20 0.40
GLA P06280 1/20 0.40
MITF O75030 1/20 0.40
RAD52 P43351 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3417208 0.84 MAPK1 (0.47) MAPK1SMN1; SMN2NPSR1MEN1KMT2A
SCHEMBL29630093 0.81 MAPK1 (0.47) MAPK1SMN1; SMN2NPSR1MEN1KMT2A
SCHEMBL778350 0.81 MAPK1 (0.47) MAPK1SMN1; SMN2NPSR1MEN1KMT2A
SCHEMBL10578179 0.81 CNR2 (0.38) MAPK1SMN1; SMN2NPSR1MEN1KMT2A
SCHEMBL5053444 0.80 MAPK1 (0.44) MAPK1SMN1; SMN2NPSR1MEN1KMT2A
SCHEMBL5551931 0.79 MAPK1 (0.55) MAPK1SMN1; SMN2NPSR1MEN1KMT2A
SCHEMBL7452935 0.78 SHBG (0.47) MAPK1SMN1; SMN2NPSR1MEN1KMT2A
SCHEMBL8765074 0.78 MAPK1 (0.46) MAPK1SMN1; SMN2NPSR1MEN1KMT2A
SCHEMBL27984663 0.77 MAPK1 (0.49) MAPK1SMN1; SMN2NPSR1MEN1KMT2A
SCHEMBL7452938 0.77 CNR2 (0.49) CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 791 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7842744-B2 excellent in ultraviolet absorption capability at 380 nm with little bleed-out; resin and an absorber, which is a tris/2-hydroxyphenyl/ triazine compound ADEKA CORPORATION (JP) 2010-11-30 US claimed
US-20090258976-A1 excellent in ultraviolet absorption capability at 380 nm with little bleed-out; resin and an absorber, which is a tris/2-hydroxyphenyl/ triazine compound NEGISHI YOSHINORI 2009-10-15 US claimed
US-7553892-B2 excellent in ultraviolet absorption capability at 380 nm with little bleed-out; resin and an absorber, which is a tris/2-hydroxyphenyl/ triazine compound ADEKA CORPORATION (JP) 2009-06-30 US claimed
US-6657083-B2 Photographic couplers; acylation amine group in position 2 EASTMAN KODAK COMPANY 2003-12-02 US claimed
US-6613943-B2 Intermediates for 4-substituted-2,5-diaminophenol derivatives as phenolic cyan couplers for color photography; deblocking the 2-acyl group by hydrolysis EASTMAN KODAK COMPANY 2003-09-02 US claimed
US-20030109716-A1 5-ACYLAMINO-2-AMINO-4-SUBSTITUTED-PHENOL COMPOUNDS AND METHOD OF USING THEM EASTMAN KODAK COMPANY 2003-06-12 US claimed
US-20030109753-A1 4-acylamino-2-hydroxy-5-substituted-acylanilide compounds and method of using them EASTMAN KODAK COMPANY 2003-06-12 US claimed
EP-1316550-A1 6-Acylamino-5-substituted-benzoxazol-2-one compounds and method for using them EASTMAN KODAK COMPANY (US) 2003-06-04 EP claimed
EP-1316544-A1 5-acylamino-2-amino-4-substituted-phenol compounds and method of using them EASTMAN KODAK COMPANY (US) 2003-06-04 EP claimed
US-6525219-B1 Chemical intermediates for cyan dye forming couplers; deblocking, hydrolysis, acylation EASTMAN KODAK COMPANY 2003-02-25 US claimed
US-6482953-B1 2-benzyloxy-4-nitro-5-substituted-acylanilide compounds and method of using them EASTMAN KODAK COMPANY 2002-11-19 US claimed
US-6476202-B1 5-acylamino-2-arylazo, nitro, or nitroso-4-substituted-phenol compounds and method of using them EASTMAN KODAK COMPANY 2002-11-05 US claimed
EP-0823068-B1 COLOR-PROVIDING COMPOUNDS POLAROID CORP (US) 2000-08-09 EP claimed
US-5948607-A DYE FORMING COUPLER; EXCELLENT IN COLOR REPRODUCIBILITY, SHARPNESS AND COLOR IMAGE FASTNESS. FUJI PHOTO FILM CO., LTD. (JP) 1999-09-07 US claimed
EP-0823068-A1 COLOR-PROVIDING COMPOUNDS POLAROID CORPORATION (US) 1998-02-11 EP claimed
US-5717079-A CONTAINING AT LEAST TWO 1,3-SULFUR-NITROGEN MOIETIES AND A COMPLETE DYE OR DYE INTERMEDIATE POLAROID CORPORATION (US) 1998-02-10 US claimed
WO-1997031295-A1 COLOR-PROVIDING COMPOUNDS POLAROID CORPORATION (US) 1997-08-28 WO claimed
US-5585227-A CONTAINING SPECIFIED YELLOW DYE-FORMING COUPLER AND CYAN COUPLER; REDUCED STAINING DURING PROCESSING AND STORAGE FUJI PHOTO FILM CO., LTD. (JP) 1996-12-17 US claimed
US-5557003-A SOLVENT EXTRACTION OF ZINC FROM ORE ZENECA LIMITED (GB) 1996-09-17 US claimed
US-5409808-A Excellent sensitivity and gradation; improved storage stability FUJI PHOTO FILM CO., LTD. (JP) 1995-04-25 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030109753-A1 4-acylamino-2-hydroxy-5-substituted-acylanilide compounds and method of using them CBR3, AADAC, HAAO MAPK1 4592/4885SMN1; SMN2 4411/4885NPSR1 405/4885
US-20030109716-A1 5-ACYLAMINO-2-AMINO-4-SUBSTITUTED-PHENOL COMPOUNDS AND METHOD OF USING THEM AADAT, AAAS, ANXA7 MAPK1 4456/4885SMN1; SMN2 3824/4885NPSR1 757/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.