Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NQO2 | P16083 | 1/20 | 0.31 |
| ▸ | PRKDC | P78527 | 1/20 | 0.31 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7089567 | 0.69 | BIRC5 (0.40) | RAB9AALDH1A1NPC1MAPT | |
| SCHEMBL4357698 | 0.61 | PRKDC (0.36) | RAB9AALDH1A1NPC1POLBMAPT | |
| SCHEMBL721718 | 0.60 | SMN1; SMN2 (0.44) | KDM4ELMNAPKMRAB9AALDH1A1 | |
| Hydrochloric Acid SCHEMBL9937226 | 0.59 | SMN1; SMN2 (0.43) | KDM4ELMNAPKMRAB9AALDH1A1 | |
| SCHEMBL4340657 | 0.59 | ALDH1A1 (0.61) | PKMALDH1A1HPGDPOLBMAPT | |
| SCHEMBL4344550 | 0.59 | ALDH1A1 (0.61) | PKMALDH1A1HPGDPOLBMAPT | |
| SCHEMBL76097 | 0.58 | CYP2E1 (0.58) | LMNAPKMRAB9AALDH1A1HPGD | |
| SCHEMBL27736349 | 0.58 | ALDH1A1 (0.42) | ALDH1A1HPGDNQO2CYP2E1CYP3A4 | |
| SCHEMBL11668799 | 0.58 | ASAH1 (0.42) | KDM4ERAB9AALDH1A1HPGDNPC1 | |
| SCHEMBL3415966 | 0.57 | ALDH1A1 (0.67) | KDM4ELMNAPKMRAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008085008-A1 | T-CELL INHIBITING COMPOUNDS AND THEIR USE FOR THE TREATMENT OF T-CELL-MEDIATED DISEASES | MOGAM BIOTECHNOLOGY RESEARCH INSTITUTE (KR) | 2008-07-17 | — | — | WO | disclosed |