Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | KIT | P10721 | 2/20 | 0.47 |
| ▸ | CKS1B | P61024 | 2/20 | 0.42 |
| ▸ | SKP1 | P63208 | 2/20 | 0.42 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.42 |
| ▸ | HPGDS | O60760 | 3/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4785878 | 0.80 | KIT (0.48) | KITCKS1BSKP1SKP2HPGDS | |
| SCHEMBL2954681 | 0.71 | TSHR (0.51) | HTTATMCKS1BSKP1SKP2 | |
| SCHEMBL2104155 | 0.69 | DRD2 (0.56) | KITHPGDSGPR119KDM4EPKM | |
| SCHEMBL18135537 | 0.69 | ALOX15 (0.54) | HTTATMCKS1BSKP1SKP2 | |
| SCHEMBL3964155 | 0.67 | DRD2 (0.54) | KITHPGDSGPR119 | |
| SCHEMBL4546718 | 0.67 | HTT (0.54) | HTTATMMEN1MAPTKMT2A | |
| SCHEMBL17708312 | 0.67 | HTT (0.54) | HTTATMMEN1MAPTKMT2A | |
| SCHEMBL3720687 | 0.67 | HTT (0.54) | HTTATMMEN1MAPTKMT2A | |
| SCHEMBL25229063 | 0.66 | CHRM1 (0.51) | HTTATMCKS1BSKP1SKP2 | |
| SCHEMBL25270944 | 0.66 | CHRM1 (0.51) | HTTATMCKS1BSKP1SKP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008085008-A1 | T-CELL INHIBITING COMPOUNDS AND THEIR USE FOR THE TREATMENT OF T-CELL-MEDIATED DISEASES | MOGAM BIOTECHNOLOGY RESEARCH INSTITUTE (KR) | 2008-07-17 | — | — | WO | claimed |
| WO-2008085008-A1 | T-CELL INHIBITING COMPOUNDS AND THEIR USE FOR THE TREATMENT OF T-CELL-MEDIATED DISEASES | MOGAM BIOTECHNOLOGY RESEARCH INSTITUTE (KR) | 2008-07-17 | — | — | WO | disclosed |