Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 5/20 | 0.37 |
| ▸ | BRAF | P15056 | 6/20 | 0.37 |
| ▸ | RAF1 | P04049 | 2/20 | 0.37 |
| ▸ | ARAF | P10398 | 2/20 | 0.37 |
| ▸ | UBE2M | P61081 | 1/20 | 0.36 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4232012 | 0.88 | EPHX2 (0.39) | MCHR1BRAFRAF1ARAFUBE2M | |
| SCHEMBL4229247 | 0.86 | MCHR1 (0.45) | MCHR1KDM4EMEN1KMT2ANPC1 | |
| SCHEMBL4237055 | 0.84 | MCHR1 (0.44) | MCHR1MEN1MAPTKMT2ANPC1 | |
| SCHEMBL4237367 | 0.82 | MCHR1 (0.39) | MCHR1MEN1MAPTKMT2A | |
| SCHEMBL4238808 | 0.82 | MCHR1 (0.42) | MCHR1KDM4EMEN1MAPTKMT2A | |
| SCHEMBL4228419 | 0.81 | MCHR1 (0.41) | MCHR1KDM4EMEN1KMT2ANPC1 | |
| SCHEMBL4240029 | 0.81 | MCHR1 (0.43) | MCHR1KDM4EMEN1MAPTKMT2A | |
| SCHEMBL4235444 | 0.81 | MCHR1 (0.40) | MCHR1KDM4EKMT2ANPC1RAB9A | |
| SCHEMBL4233302 | 0.80 | PKM (0.38) | MCHR1BRAFKDM4EMEN1MAPT | |
| SCHEMBL4226989 | 0.80 | TAS1R3 (0.39) | MCHR1CYP2C19KDRNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879887-A2 | NPY ANTAGONISTS, PREPARATION AND USE | Cerep (FR) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006108965-A2 | NPY ANTAGONISTS, PREPARATION AND USE | CEREP (FR) | 2006-10-19 | — | — | WO | disclosed |