Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | LTB4R | Q15722 | 3/20 | 0.49 |
| ▸ | LTB4R2 | Q9NPC1 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | DHFR | P00374 | 1/20 | 0.47 |
| ▸ | PTGER1 | P34995 | 4/20 | 0.47 |
| ▸ | PTGER4 | P35408 | 4/20 | 0.47 |
| ▸ | PTGER3 | P43115 | 4/20 | 0.47 |
| ▸ | PTGER2 | P43116 | 4/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29874929 | 0.83 | L3MBTL1 (0.57) | LTB4RLMNAL3MBTL1POLBSMN1; SMN2 | |
| SCHEMBL1884182 | 0.83 | L3MBTL1 (0.57) | LTB4RLMNAL3MBTL1POLBSMN1; SMN2 | |
| SCHEMBL1208625 | 0.83 | L3MBTL1 (0.59) | THRATHRBNPSR1LTB4RLTB4R2 | |
| SCHEMBL362209 | 0.83 | LMNA (0.59) | NPSR1LMNAFFAR1POLBSMN1; SMN2 | |
| SCHEMBL29590071 | 0.83 | LMNA (0.59) | NPSR1LMNAFFAR1POLBSMN1; SMN2 | |
| SCHEMBL22382257 | 0.82 | ABCB1 (0.51) | — | |
| SCHEMBL16972794 | 0.82 | CYP4F2 (0.60) | LMNADHFRPOLBSMN1; SMN2 | |
| SCHEMBL28185335 | 0.82 | FFAR4 (0.52) | THRATHRBNPSR1LTB4RLTB4R2 | |
| SCHEMBL28209378 | 0.82 | FFAR4 (0.55) | LTB4RLTB4R2PTGER1PTGER4PTGER3 | |
| SCHEMBL7340039 | 0.81 | L3MBTL1 (0.63) | THRATHRBNPSR1LTB4RLTB4R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101015544-B | Use of phenyl propyl compound with oxidation resistance function for protecting liver and brain damage | ZHEJIANG HISUN PHARM CO LTD | 2010-07-07 | — | — | CN | disclosed |
| EP-1960518-A2 | ANTIBACTERIAL AGENTS | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2008-08-27 | — | — | EP | disclosed |
| CN-101015544-A | Use of phenyl propyl compound with oxidation resistance function for protecting liver and brain damage | ZHEJIANG HISUN NATURSITE PHARM (CN) | 2007-08-15 | — | — | CN | disclosed |
| WO-2007067559-A2 | ANTIBACTERIAL AGENTS | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2007-06-14 | — | — | WO | disclosed |