Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CTSK | P43235 | 7/20 | 0.43 |
| ▸ | CTSS | P25774 | 5/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | SYK | P43405 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1262597 | 1.00 | MEN1 (0.47) | MEN1GAAKMT2ACTSKCTSS | |
| SCHEMBL6945578 | 1.00 | MEN1 (0.47) | MEN1GAAKMT2ACTSKCTSS | |
| SCHEMBL1105702 | 0.87 | PCSK9 (0.50) | MEN1GAAKMT2ACTSKCTSS | |
| SCHEMBL21452652 | 0.86 | MEN1 (0.44) | MEN1GAAKMT2ACTSKCTSS | |
| SCHEMBL21452654 | 0.86 | MEN1 (0.44) | MEN1GAAKMT2ACTSKCTSS | |
| SCHEMBL24363894 | 0.84 | MEN1 (0.42) | MEN1GAAKMT2ACTSKCTSS | |
| SCHEMBL7758385 | 0.84 | MEN1 (0.42) | MEN1GAAKMT2ACTSKCTSS | |
| SCHEMBL7759432 | 0.84 | MEN1 (0.42) | MEN1GAAKMT2ACTSKCTSS | |
| SCHEMBL3423364 | 0.84 | CYP2D6 (0.43) | MEN1GAAKMT2ACTSKCTSS | |
| SCHEMBL13906658 | 0.84 | MEN1 (0.49) | MEN1GAAKMT2ACTSKCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102015699-A | Heterocyclic urea derivatives and methods of use thereof-211 | ASTRAZENECA AB | 2011-04-13 | — | — | CN | disclosed |
| WO-2008093960-A1 | NOVEL DIPEPTIDYL PEPTIDASE-IV INHIBITORS | LG LIFE SCIENCES, LTD. (KR) | 2008-08-07 | — | — | WO | disclosed |