Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 10/20 | 0.67 |
| ▸ | NPC1 | O15118 | 9/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.67 |
| ▸ | LMNA | P02545 | 5/20 | 0.67 |
| ▸ | MAPT | P10636 | 4/20 | 0.67 |
| ▸ | HTT | P42858 | 4/20 | 0.67 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.67 |
| ▸ | PAX8 | Q06710 | 3/20 | 0.67 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.67 |
| ▸ | XBP1 | P17861 | 3/20 | 0.55 |
| ▸ | MAPK14 | Q16539 | 5/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | TDO2 | P48775 | 1/20 | 0.41 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1749910 | 0.84 | RAB9A (0.60) | RAB9ANPC1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL4191587 | 0.83 | NPC1 (0.69) | RAB9ANPC1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL31278205 | 0.82 | RAB9A (0.68) | RAB9ANPC1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL3034789 | 0.82 | RAB9A (0.68) | RAB9ANPC1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL3039672 | 0.81 | MAPT (0.61) | RAB9ANPC1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL4187625 | 0.81 | SMN1; SMN2 (0.71) | RAB9ANPC1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL4743412 | 0.80 | RAB9A (1.00) | RAB9ANPC1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL4191812 | 0.80 | RAB9A (0.60) | RAB9ANPC1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL3028836 | 0.79 | ALDH1A1 (0.63) | RAB9ANPC1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL2894395 | 0.78 | ALDH1A1 (0.66) | RAB9ANPC1ALDH1A1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008101615-A1 | METHOD FOR PRODUCING 4,5-DIHALOGEN-2-ARYL-2H-PYRIDAZIN-3-ONES | BAYER ANIMAL HEALTH GMBH (DE) | 2008-08-28 | — | — | WO | disclosed |