SCHEMBL474095

SCHEMBL474095

O=C(/C=C/c1ccccc1)OOOC(=O)/C=C/c1ccccc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.59
LMNA P02545 3/20 0.59
ALDH1A1 P00352 3/20 0.59
HDAC3 O15379 2/20 0.59
HDAC4 P56524 2/20 0.59
HDAC1 Q13547 2/20 0.59
HDAC2 Q92769 2/20 0.59
HDAC8 Q9BY41 2/20 0.59
HDAC6 Q9UBN7 2/20 0.59
PLIN1 O60240 2/20 0.59
RECQL P46063 2/20 0.59
PLIN5 Q00G26 2/20 0.59
ABHD5 Q8WTS1 2/20 0.59
F3 P13726 2/20 0.59
TNKS O95271 1/20 0.59
HCAR2 Q8TDS4 1/20 0.59
HDAC7 Q8WUI4 1/20 0.59
HDAC10 Q969S8 1/20 0.59
HDAC11 Q96DB2 1/20 0.59
TNKS2 Q9H2K2 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15950322 1.00 MAPT (0.59) MAPTLMNAALDH1A1HDAC3HDAC4
SCHEMBL869265 0.91 MAPT (0.64) MAPTLMNAALDH1A1HDAC3HDAC4
SCHEMBL869266 0.91 MAPT (0.64) MAPTLMNAALDH1A1HDAC3HDAC4
SCHEMBL320925 0.84 TDP1 (0.57) MAPTLMNAALDH1A1HDAC3HDAC4
SCHEMBL320924 0.84 TDP1 (0.57) MAPTLMNAALDH1A1HDAC3HDAC4
SCHEMBL29198288 0.83 MAPT (0.59) MAPTLMNAALDH1A1HDAC3HDAC4
SCHEMBL9247555 0.83 MAPT (0.64) MAPTLMNAALDH1A1HDAC3HDAC4
SCHEMBL21803794 0.83 MAPT (0.64) MAPTLMNAALDH1A1HDAC3HDAC4
SCHEMBL775716 0.83 MAPT (0.64) MAPTLMNAALDH1A1HDAC3HDAC4
SCHEMBL908549 0.82 MAPT (0.53) MAPTLMNAALDH1A1HDAC3HDAC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113873769-B Method for avoiding solder mask printing ink from being applied to bonding pad 广东喜珍电路科技有限公司 2023-11-03 CN claimed
CN-113873769-A Method for avoiding solder mask ink from bonding pad 奥士康精密电路(惠州)有限公司 2021-12-31 CN claimed
CN-113873769-B Method for avoiding solder mask printing ink from being applied to bonding pad 广东喜珍电路科技有限公司 2023-11-03 CN disclosed
CN-113873769-A Method for avoiding solder mask ink from bonding pad 奥士康精密电路(惠州)有限公司 2021-12-31 CN disclosed
EP-1348696-B1 Use of optically active clausenamides for the preparation of pharmaceutical compositions, pharmaceutical compositions containing the same INST MATERIA MEDICA CAMS (CN) 2012-02-01 EP disclosed
CN-1250546-C Tetrahydropyrido compound ALTANA PHARMA (DE) 2006-04-12 CN disclosed
US-6787564-B2 FOR TREATING HYPOXIA PROTECTIVE, NOOTROPIC AND NEURODEGENERATIVE DISEASES (CERBRAL ISCHEMIA, ALZHEIMER'S DISEASE, AND VASCULAR DEMENTIA) INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF MEDICAL SCIENCES (CN) 2004-09-07 US disclosed
CN-1508136-A Tetrahydropyrido compound ��̹��ҽҩ��˾ 2004-06-30 CN disclosed
US-20030207935-A1 Novel optically active clausenamides, process of the preparation thereof, pharmaceutical composition containing the same and their medical use INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF MEDICAL SCIENCES 2003-11-06 US disclosed
EP-1348696-A1 Optically active clausenamides, process of the preparation thereof, pharmaceutical composition containing the same and their medical use INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF MEDICAL SCIENCES (CN) 2003-10-01 EP disclosed
CN-1251102-A Tetrahydropyrido compounds BYK GULDEN LOMBERG CHEM FAB (DE) 2000-04-19 CN disclosed
US-4920038-A Printed circuit manufacture employing a radiation cross-linkable photo-polymer system SIEMENS AKTIENGESELLSCHAFT 1990-04-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030207935-A1 Novel optically active clausenamides, process of the preparation thereof, pharmaceutical composition containing the same and their medical use HIF1AN, HIF1A, CLN6 MAPT 59/4885LMNA 511/4885ALDH1A1 1464/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.