SCHEMBL775716

SCHEMBL775716

O=C(C=Cc1ccccc1)OC(=O)C=Cc1ccccc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.64
LMNA P02545 3/20 0.64
ALDH1A1 P00352 3/20 0.64
HDAC3 O15379 2/20 0.64
HDAC4 P56524 2/20 0.64
HDAC1 Q13547 2/20 0.64
HDAC2 Q92769 2/20 0.64
HDAC8 Q9BY41 2/20 0.64
HDAC6 Q9UBN7 2/20 0.64
PLIN1 O60240 2/20 0.64
RECQL P46063 2/20 0.64
PLIN5 Q00G26 2/20 0.64
ABHD5 Q8WTS1 2/20 0.64
F3 P13726 2/20 0.64
TNKS O95271 1/20 0.64
HCAR2 Q8TDS4 1/20 0.64
HDAC7 Q8WUI4 1/20 0.64
HDAC10 Q969S8 1/20 0.64
HDAC11 Q96DB2 1/20 0.64
TNKS2 Q9H2K2 1/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21803794 1.00 MAPT (0.64) MAPTLMNAALDH1A1HDAC3HDAC4
SCHEMBL9247555 1.00 MAPT (0.64) MAPTLMNAALDH1A1HDAC3HDAC4
SCHEMBL29198288 0.91 MAPT (0.59) MAPTLMNAALDH1A1HDAC3HDAC4
SCHEMBL27483295 0.90 HDAC2 (0.61) MAPTLMNAALDH1A1HDAC3HDAC4
SCHEMBL27541700 0.90 KMT2A (0.75) MAPTLMNAALDH1A1HDAC3HDAC4
SCHEMBL13837132 0.90 AKR1B10 (0.66) MAPTLMNAALDH1A1HDAC3HDAC4
SCHEMBL11317973 0.90 HDAC3 (0.58) MAPTLMNAALDH1A1HDAC3HDAC4
SCHEMBL775717 0.90 MAPT (0.53) MAPTLMNAALDH1A1HDAC3HDAC4
SCHEMBL3763449 0.90 MAPT (0.53) MAPTLMNAALDH1A1HDAC3HDAC4
SCHEMBL27497954 0.89 MAPT (0.62) MAPTLMNAALDH1A1HDAC3HDAC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 338 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111072614-B Lipid wax flavored tobacco sweetener, preparation method and application thereof in cigarettes 河南中烟工业有限责任公司 2023-07-18 CN claimed
CN-114292350-B Hemicellulose cinnamate, preparation method thereof and application thereof in biodegradable composite material 南京工业大学 2023-03-03 CN claimed
CN-113083031-B Electrically neutral polyvinylidene fluoride ultrafiltration membrane and preparation method thereof 贵州省材料产业技术研究院 2022-12-23 CN claimed
CN-113083032-B Positively charged blended ultrafiltration membrane and preparation method thereof 贵州省材料产业技术研究院 2022-10-28 CN claimed
CN-114292350-A Hemicellulose cinnamate, preparation method thereof and application thereof in biodegradable composite material 南京工业大学 2022-04-08 CN claimed
CN-114016332-A Antibacterial waterproof packaging paper and preparation method thereof 南通德润包装制品有限公司 2022-02-08 CN claimed
CN-113083031-A Electrically neutral polyvinylidene fluoride ultrafiltration membrane and preparation method thereof 贵州省材料产业技术研究院 2021-07-09 CN claimed
US-20260147287-A1 TWO-COMPONENT DEVELOPER CANON KABUSHIKI KAISHA (JP) 2026-05-28 US disclosed
CN-122085625-A Two-component developer 2026-05-26 CN disclosed
EP-4743525-A1 RELEASE COATING FOR TAPES Dow Global Technologies LLC (US) 2026-05-20 EP disclosed
CN-122043891-A Toner and method for producing the same 佳能株式会社 2026-05-15 CN disclosed
EP-4735552-A1 ADHESIVE COMPOSITION DOW GLOBAL TECHNOLOGIES LLC (US) 2026-05-06 EP disclosed
US-12620622-B2 Compound including sulfur-containing heterocyclic cation and bis(oxolato)borate anion, electrolytic solution and electrochemical device including the same DAIKIN INDUSTRIES, LTD. (JP) 2026-05-05 US disclosed
EP-0719291-B1 NOVEL FUNCTIONALIZED ISOOLEFIN/PARA-ALKYLSTYRENE COPOLYMERS EXXON RESEARCH ENGINEERING CO (US) 1998-05-20 EP disclosed
EP-0719291-A4 NOVEL FUNCTIONALIZED ISOOLEFIN/PARA-ALKYLSTYRENE COPOLYMERS EXXON RESEARCH ENGINEERING CO (US) 1996-08-21 EP disclosed
EP-0719291-A1 NOVEL FUNCTIONALIZED ISOOLEFIN/PARA-ALKYLSTYRENE COPOLYMERS EXXON RESEARCH AND ENGINEERING COMPANY (US) 1996-07-03 EP disclosed
WO-1995007945-A1 NOVEL FUNCTIONALIZED ISOOLEFIN/PARA-ALKYLSTYRENE COPOLYMERS EXXON RESEARCH & ENGINEERING COMPANY (US) 1995-03-23 WO disclosed
US-4767451-A STEEL PRODUCTION, POLYMERIC ARC STABILIZER DONCAR INCORPORATED (US) 1988-08-30 US disclosed
EP-0187008-A2 Composition and method for producing a heat of steel Bergman, Donald George (US) 1986-07-09 EP disclosed
US-3935342-A POLYMERIZATION WITH AN UNSATURATED SILYL MONOMER MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) 1976-01-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260147287-A1 TWO-COMPONENT DEVELOPER SMARCB1, HBB, SMARCA2 MAPT 2307/4885LMNA 867/4885ALDH1A1 4732/4885
US-12620622-B2 Compound including sulfur-containing heterocyclic cation and bis(oxolato)borate anion, electrolytic solution and electrochemical device including the same ASH2L, OLA1, ODC1 MAPT 3870/4885LMNA 3780/4885ALDH1A1 1584/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.