SCHEMBL908549

SCHEMBL908549

C=C(C=Cc1ccccc1)C(=O)OOOC(=O)C(=C)C=Cc1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.53
ALDH1A1 P00352 4/20 0.53
LMNA P02545 3/20 0.53
HDAC3 O15379 2/20 0.53
HDAC4 P56524 2/20 0.53
HDAC1 Q13547 2/20 0.53
HDAC2 Q92769 2/20 0.53
HDAC8 Q9BY41 2/20 0.53
HDAC6 Q9UBN7 2/20 0.53
PLIN1 O60240 2/20 0.53
RECQL P46063 2/20 0.53
PLIN5 Q00G26 2/20 0.53
ABHD5 Q8WTS1 2/20 0.53
F3 P13726 2/20 0.53
TNKS O95271 1/20 0.53
HCAR2 Q8TDS4 1/20 0.53
HDAC7 Q8WUI4 1/20 0.53
HDAC10 Q969S8 1/20 0.53
HDAC11 Q96DB2 1/20 0.53
TNKS2 Q9H2K2 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10824208 0.84 MAPT (0.52) MAPTALDH1A1LMNAHDAC3HDAC4
SCHEMBL4304845 0.84 LMNA (0.52) MAPTALDH1A1LMNAHDAC3HDAC4
SCHEMBL2335380 0.84 MAPT (0.52) MAPTALDH1A1LMNAHDAC3HDAC4
SCHEMBL225081 0.84 ALDH1A1 (0.54) MAPTALDH1A1LMNAHDAC3HDAC4
SCHEMBL15950322 0.82 MAPT (0.59) MAPTALDH1A1LMNAHDAC3HDAC4
SCHEMBL474095 0.82 MAPT (0.59) MAPTALDH1A1LMNAHDAC3HDAC4
SCHEMBL11307419 0.82 MAPT (0.50) MAPTALDH1A1LMNAHDAC3HDAC4
SCHEMBL5583507 0.82 MAPT (0.50) MAPTALDH1A1LMNAHDAC3HDAC4
SCHEMBL27487053 0.81 GLA (0.55) MAPTALDH1A1LMNAHDAC3HDAC4
SCHEMBL27695239 0.81 LMNA (0.49) MAPTALDH1A1LMNAHDAC3HDAC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0612826-A1 Electrochromic polymeric solid films, manufacturing electrochromic devices using such solid films, and processing for making such solid films and devices DONNELLY CORPORATION (US) 1994-08-31 EP claimed
US-8610992-B2 Variable transmission window DONNELLY CORPORATION (US) 2013-12-17 US disclosed
US-8559093-B2 Electrochromic mirror reflective element for vehicular rearview mirror assembly DONNELLY CORPORATION (US) 2013-10-15 US disclosed
US-8511841-B2 Vehicular blind spot indicator mirror DONNELLY CORPORATION (US) 2013-08-20 US disclosed
US-20130063802-A1 VARIABLE TRANSMISSION WINDOW DONNELLY CORPORATION (US) 2013-03-14 US disclosed
US-8294975-B2 Automotive rearview mirror assembly DONNELLY CORPORATION (US) 2012-10-23 US disclosed
US-20120206790-A1 ELECTROCHROMIC MIRROR REFLECTIVE ELEMENT FOR VEHICULAR REARVIEW MIRROR ASSEMBLY DONNELLY CORPORATION (US) 2012-08-16 US disclosed
US-8164817-B2 Method of forming a mirrored bent cut glass shape for vehicular exterior rearview mirror assembly DONNELLY CORPORATION (US) 2012-04-24 US disclosed
US-20110128137-A1 VEHICULAR BLIND SPOT INDICATOR MIRROR DONNELLY CORPORATION (US) 2011-06-02 US disclosed
US-20110045172-A1 METHOD OF FORMING A MIRRORED BENT CUT GLASS SHAPE FOR VEHICULAR EXTERIOR REARVIEW MIRROR ASSEMBLY DONNELLY CORPORATION (US) 2011-02-24 US disclosed
US-20020012156-A1 Electrochromic polymeric solid films, manufacturing electrochromic devices using such solid films, and processes for making such solid films and devices VARAPRASAD DESARAJU V (US) 2002-01-31 US disclosed
US-6245262-B1 Electrochromic polymeric solid films, manufacturing electrochromic devices using such solid films, and processes for making such films and devices DONNELLY CORPORATION 2001-06-12 US disclosed
US-6154306-A Electrochromic polymeric solid films, manufacturing electrochromic devices using such solid films, and processes for making such solid films and devices DONNELLY CORPORATION (US) 2000-11-28 US disclosed
EP-0612826-B1 Electrochromic polymeric solid films, manufacturing electrochromic devices using such solid films, and processing for making such solid films and devices DONNELLY CORP (US) 2000-10-04 EP disclosed
EP-1004649-A2 Electrochromic polymeric solid films, manufacturing electrochromic devices using such solid films, and processes for making such solid films and devices DONNELLY CORPORATION (US) 2000-05-31 EP disclosed
EP-0975709-A1 ELECTROCHROMIC POLYMERIC SOLID FILMS, MANUFACTURING ELECTROCHROMIC DEVICES USING SUCH SOLID FILMS, AND PROCESSES FOR MAKING SUCH SOLID FILMS AND DEVICES DONNELLY CORPORATION (US) 2000-02-02 EP disclosed
US-6002511-A Electrochromic polymeric solid films, manufacturing electrochromic devices using such solid films, and processes for making such solid films and devices DONNELLY CORPORATION (US) 1999-12-14 US disclosed
US-5910854-A FOR USE AS AN ARCHITECTURAL OR VEHICULAR GLAZING DONNELLY CORPORATION (US) 1999-06-08 US disclosed
WO-1998042796-A1 ELECTROCHROMIC POLYMERIC SOLID FILMS, MANUFACTURING ELECTROCHROMIC DEVICES USING SUCH SOLID FILMS, AND PROCESSES FOR MAKING SUCH SOLID FILMS AND DEVICES DONNELLY CORPORATION (US) 1998-10-01 WO disclosed
EP-0612826-A1 Electrochromic polymeric solid films, manufacturing electrochromic devices using such solid films, and processing for making such solid films and devices DONNELLY CORPORATION (US) 1994-08-31 EP disclosed