Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 10/20 | 0.60 |
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL216812 | 0.77 | MAOA (0.42) | KDRCTSLMAOAMAOB | |
| SCHEMBL216811 | 0.77 | MAOA (0.42) | KDRCTSLMAOAMAOB | |
| SCHEMBL4461043 | 0.74 | SNCA (0.52) | KDRMAOAMAOB | |
| SCHEMBL3969210 | 0.72 | APP (0.51) | KDRMAOAMAOB | |
| SCHEMBL21219011 | 0.71 | CYP1A2 (0.56) | KDRDAO | |
| SCHEMBL499507 | 0.71 | CYP1A2 (0.56) | KDRDAO | |
| SCHEMBL16048819 | 0.70 | CA1 (0.53) | — | |
| SCHEMBL16048816 | 0.70 | CA1 (0.53) | — | |
| SCHEMBL18551815 | 0.70 | MAOA (0.51) | KDRDAOMAOAMAOB | |
| SCHEMBL6781413 | 0.70 | KDR (0.52) | KDRDAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008087365-A2 | SUBSTITUTED 1, 3-DIPHENYLPROPANE DERIVATIVES, PREPARATIONS AND USES OF SAME | GENFIT (FR) | 2008-07-24 | — | — | WO | disclosed |