Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 6/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15833610 | 0.90 | HCAR1 (0.50) | HCAR1GAAHSD17B10MAPK1LRRK2 | |
| SCHEMBL17678349 | 0.89 | GAA (0.50) | GAAHSD17B10FGFR1ALDH1A1TP53 | |
| SCHEMBL18250716 | 0.86 | GAA (0.55) | HCAR1GAAHSD17B10FGFR1ALDH1A1 | |
| SCHEMBL18250724 | 0.86 | GAA (0.58) | HCAR1GAAHSD17B10FGFR1ALDH1A1 | |
| SCHEMBL18250725 | 0.84 | GAA (0.61) | HCAR1GAAHSD17B10FGFR1ALDH1A1 | |
| SCHEMBL15344915 | 0.82 | DRD2 (0.50) | GAAHSD17B10FGFR1ALDH1A1TP53 | |
| SCHEMBL15205857 | 0.82 | HCAR1 (0.48) | HCAR1GAAHSD17B10ALDH1A1MAPK1 | |
| SCHEMBL17675678 | 0.78 | JAK2 (0.45) | HCAR1GAAHSD17B10ALDH1A1MAPK1 | |
| SCHEMBL4743122 | 0.78 | DRD2 (0.44) | HCAR1GAAHSD17B10FGFR1ALDH1A1 | |
| SCHEMBL31208320 | 0.77 | GAA (0.76) | HCAR1GAAHSD17B10FGFR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008084218-A1 | BENZAZOLE DERIVATIVES FOR THE TREATMENT OF INFLAMMATIONS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-07-17 | — | — | WO | disclosed |