Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 2/20 | 0.49 |
| ▸ | PNMT | P11086 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.44 |
| ▸ | PYGL | P06737 | 1/20 | 0.44 |
| ▸ | IGF1R | P08069 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.43 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.43 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.43 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.43 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3589323 | 0.85 | FFAR1 (0.51) | FFAR1PNMTTAAR1TSHRPDPK1 | |
| SCHEMBL10540830 | 0.83 | IDO1 (0.52) | FFAR1TSHRFFAR4MEN1KMT2A | |
| SCHEMBL8103430 | 0.81 | FFAR4 (0.56) | FFAR1FFAR4TDP1 | |
| SCHEMBL14100864 | 0.79 | TSHR (0.42) | FFAR1PNMTTAAR1TSHRPDPK1 | |
| SCHEMBL3893736 | 0.79 | ALDH1A1 (0.51) | FFAR1TAAR1PLAAT3PLAAT5PLAAT2 | |
| SCHEMBL4742633 | 0.77 | PNMT (0.50) | PNMTTAAR1TSHRPYGLIGF1R | |
| SCHEMBL1206803 | 0.77 | FFAR1 (0.69) | FFAR1PNMTTAAR1PDPK1PYGL | |
| SCHEMBL8132571 | 0.75 | FFAR4 (0.52) | FFAR1FFAR4TDP1 | |
| SCHEMBL4588706 | 0.75 | CYP1A2 (0.59) | FFAR1PDPK1FFAR4 | |
| SCHEMBL3815987 | 0.75 | TSHR (0.50) | TSHRALOX15MEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008096093-A1 | OXAZOLE AND THIAZOLE DERIVATIVES AND THEIR USES | ARGENTA DISCOVERY LTD. (GB) | 2008-08-14 | — | — | WO | disclosed |