⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL8880462 | 0.97 | — | — | |
| SCHEMBL5747564 | 0.84 | CTH (0.43) | — | |
| SCHEMBL10866549 | 0.74 | — | — | |
| SCHEMBL2406065 | 0.69 | ALDH1A1 (0.36) | — | |
| SCHEMBL6866757 | 0.67 | METAP1 (0.40) | — | |
| Acetaldehyde SCHEMBL25292052 | 0.65 | — | — | |
| SCHEMBL247551 | 0.64 | — | — | |
| SCHEMBL12661447 | 0.64 | — | — | |
| SCHEMBL534208 | 0.63 | ESR1 (0.42) | — | |
| SCHEMBL9728321 | 0.63 | ALDH1A1 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 984 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119425786-A | Thiazole ring modification C3N4/C3N5Heterojunction photocatalyst and preparation method and application thereof | 中国矿业大学 | 2025-02-14 | — | — | CN | claimed |
| CN-114957171-B | Novel five-membered heterocycle substituted styrene derivative and preparation method and application thereof | 广东工业大学 | 2024-07-30 | — | — | CN | claimed |
| WO-2024149231-A1 | PARP7 INHIBITORS AND USES THEREOF | Angel Pharmaceutical Co., Ltd. (CN) | 2024-07-18 | — | — | WO | claimed |
| WO-2023246836-A1 | NOVEL FIVE-MEMBERED HETEROCYCLE SUBSTITUTED STYRENE DERIVATIVE, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 广东工业大学 | 2023-12-28 | — | — | WO | claimed |
| CN-115232070-B | Quinolinone alkaloid derivative containing acylhydrazone group on 1-position nitrogen atom, and preparation method and application thereof | 太原理工大学 | 2023-06-30 | — | — | CN | claimed |
| CN-110759903-B | Novel synthesis method of thiabendazole | 南开大学 | 2022-10-28 | — | — | CN | claimed |
| CN-115232070-A | Quinolinone alkaloid derivative containing acylhydrazone group on 1-site nitrogen atom and preparation method and application thereof | 太原理工大学 | 2022-10-25 | — | — | CN | claimed |
| EP-3331959-B1 | ANIONIC CURABLE COMPOSITIONS | DESIGNER MOLECULES INC (US) | 2022-10-05 | — | — | EP | claimed |
| CN-114957171-A | Novel five-membered heterocyclic substituted styrene derivative and preparation method and application thereof | 广东工业大学 | 2022-08-30 | — | — | CN | claimed |
| US-20220204696-A1 | PHENOLIC FUNCTIONALIZED POLYIMIDES AND COMPOSITIONS THEREOF | DESIGNER MOLECULES, INC | 2022-06-30 | — | — | US | claimed |
| EP-1351686-A2 | SUBSTITUTED POLYCYCLIC ARYL AND HETEROARYL PYRIDINES USEFUL FOR SELECTIVE INHIBITION OF THE COAGULATION CASCADE | Pharmacia Corporation (US) | 2003-10-15 | — | — | EP | claimed |
| JP-2003519135-A | — | — | 2003-06-17 | — | — | JP | claimed |
| US-6458787-B1 | NOVEL PYRROLIDINE COMPOUNDS THAT ARE POTENT AND SELECTIVE INHIBITORS OF PDE4, AS WELL AS METHODS OF MAKING THE SAME, ARE DISCLOSED. USE OF THE COMPOUNDS IN THE TREATMENT OF INFLAMMATORY DISEASES AND OTHER DISEASES INVOLVING ELEVATED | ICOS CORPORATION | 2002-10-01 | — | — | US | claimed |
| EP-1242400-A1 | PYRROLIDINE DERIVATIVES AS CYCLIC AMP-SPECIFIC PHOSPHODIESTERASE INHIBITORS | ICOS CORPORATION (US) | 2002-09-25 | — | — | EP | claimed |
| WO-2002042272-A2 | SUBSTITUTED POLYCYCLIC ARYL AND HETEROARYL PYRIDINES USEFUL FOR SELECTIVE INHIBITION OF THE COAGULATION CASCADE | PHARMACIA CORPORATION (US) | 2002-05-30 | — | — | WO | claimed |
| CN-1080720-C | Thiazole derivatives | HOFFMANN LA ROCHE (CH) | 2002-03-13 | — | — | CN | claimed |
| WO-2001047905-A1 | PYRROLIDINE DERIVATIVES AS CYCLIC AMP-SPECIFIC PHOSPHODIESTERASE INHIBITORS | ICOS CORPORATION (US) | 2001-07-05 | — | — | WO | claimed |
| CN-1224718-A | Thiazole derivatives | HOFFMANN LA ROCHE (CH) | 1999-08-04 | — | — | CN | claimed |
| US-5856556-A | Azetidinone derivatives, a process for their preparation and their use as intermediates in the preparation of carbapenem antibiotics | SANKYO COMPANY, LIMITED (JP) | 1999-01-05 | — | — | US | claimed |
| US-4125530-A | FROM 1,1-DIHALO-3,3,3-TRIFLUOROACETONE, BASE, AMMONIA AND A CARBOXALDEHYDE | MERCK & CO., INC. (US) | 1978-11-14 | — | — | US | claimed |