Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.49 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.48 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.47 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13416791 | 0.89 | FDPS (0.49) | FDPSCHRNA7CHRNB2CHRNA4CYP2A6 | |
| SCHEMBL290633 | 0.85 | SLC6A2 (0.57) | FDPSCHRNA7CHRNB2CHRNA4CYP2A6 | |
| SCHEMBL12894954 | 0.85 | SLC6A2 (0.57) | FDPSCHRNA7CHRNB2CHRNA4CYP2A6 | |
| SCHEMBL29669201 | 0.85 | SLC6A2 (0.57) | FDPSCHRNA7CHRNB2CHRNA4CYP2A6 | |
| SCHEMBL21947449 | 0.81 | FDPS (0.53) | FDPSCHRNA7CHRNB2CHRNA4CYP2A6 | |
| SCHEMBL20038719 | 0.81 | FDPS (0.53) | FDPSCHRNA7CHRNB2CHRNA4CYP2A6 | |
| SCHEMBL103883 | 0.80 | FDPS (0.55) | FDPSCHRNA7CHRNB2CHRNA4CYP2D6 | |
| SCHEMBL19079574 | 0.80 | FDPS (0.47) | FDPSCHRNA7CHRNB2CHRNA4CYP2A6 | |
| SCHEMBL19079571 | 0.80 | FDPS (0.47) | FDPSCHRNA7CHRNB2CHRNA4CYP2A6 | |
| SCHEMBL19079576 | 0.80 | FDPS (0.47) | FDPSCHRNA7CHRNB2CHRNA4CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008109613-A1 | BENZO[C][2,7]NAPHTHYRIDINE DERIVATIVES, AND THEIR USE AS KINASE INHIBITORS | WYETH (US) | 2008-09-12 | — | — | WO | disclosed |