Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.57 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.57 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.57 |
| ▸ | MAOA | P21397 | 1/20 | 0.57 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.57 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.57 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.57 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.57 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.57 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.52 |
| ▸ | FDPS | P14324 | 1/20 | 0.51 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.50 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.50 |
| ▸ | PNMT | P11086 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL290633 | 1.00 | SLC6A2 (0.57) | SLC6A2TAAR1CYP2A6MAOASLC6A4 | |
| SCHEMBL12894954 | 1.00 | SLC6A2 (0.57) | SLC6A2TAAR1CYP2A6MAOASLC6A4 | |
| SCHEMBL4957635 | 0.85 | FDPS (0.46) | SLC6A2TAAR1CYP2A6MAOASLC6A4 | |
| SCHEMBL13416791 | 0.85 | FDPS (0.49) | CYP2A6CHRNA7FDPSCHRNB2CHRNA4 | |
| SCHEMBL4741562 | 0.85 | FDPS (0.49) | CYP2A6CHRNA7FDPSCHRNB2CHRNA4 | |
| SCHEMBL4959182 | 0.84 | FDPS (0.45) | SLC6A2TAAR1CYP2A6MAOASLC6A4 | |
| SCHEMBL103883 | 0.83 | FDPS (0.55) | CHRNA7FDPSCHRNB2CHRNA4CYP1A2 | |
| SCHEMBL19079574 | 0.83 | FDPS (0.47) | CYP2A6CHRNA7FDPSCHRNB2CHRNA4 | |
| SCHEMBL19079571 | 0.83 | FDPS (0.47) | CYP2A6CHRNA7FDPSCHRNB2CHRNA4 | |
| SCHEMBL19079576 | 0.83 | FDPS (0.47) | CYP2A6CHRNA7FDPSCHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11424006-B2 | Targeted drugs associated with trimethylamine and/or trimeihylamine-n-oxide | PSOMAGEN, INC. (US) | 2022-08-23 | — | — | US | disclosed |
| CN-110325531-B | Benzenesulfonamides and their use as therapeutic agents | 泽农医药公司 | 2022-05-27 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11424006-B2 | Targeted drugs associated with trimethylamine and/or trimeihylamine-n-oxide | PNMT, MAOA, HNMT | SLC6A2 97/4885TAAR1 66/4885CYP2A6 240/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.