SCHEMBL4742312

SCHEMBL4742312

CC(=O)NCCn1c(O)c(/N=N/c2c(C#N)cnn2-c2ncccn2)c(C)c(C#N)c1=O

nearest known ligand 0.37

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 0.37
KMT2A Q03164 5/20 0.37
MAPT P10636 4/20 0.37
CYP3A4 P08684 1/20 0.33
CYP2C19 P33261 1/20 0.33
ALDH1A1 P00352 2/20 0.33
PKM P14618 1/20 0.33
KDM4E B2RXH2 1/20 0.33
MITF O75030 1/20 0.33
THRB P10828 1/20 0.33
LMNA P02545 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4743198 0.84 MAPT (0.38) MEN1KMT2AMAPTALDH1A1PKM
SCHEMBL4742259 0.84 MAPT (0.38) MEN1KMT2AMAPTALDH1A1PKM
SCHEMBL14231376 0.77 KMT2A (0.41) MEN1KMT2AMAPTALDH1A1PKM
SCHEMBL13996806 0.77 KMT2A (0.41) MEN1KMT2AMAPTALDH1A1PKM
SCHEMBL4781146 0.75 MAPT (0.40) MEN1KMT2AMAPTCYP2C19ALDH1A1
SCHEMBL4742276 0.75 KMT2A (0.41) MEN1KMT2AMAPTLMNASMN1; SMN2
SCHEMBL4742314 0.74 MAPT (0.39) MEN1KMT2AMAPTALDH1A1PKM
SCHEMBL4742303 0.72 DPP4 (0.36) MEN1KMT2AMAPTCYP2C19ALDH1A1
SCHEMBL4742592 0.72 PTGS1 (0.35) MEN1KMT2AMAPTCYP3A4CYP2C19
SCHEMBL4742302 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8177861-B2 AZO pigment, pigment dispersion containing the AZO pigment, and coloring composition FUJIFILM CORPORATION (JP) 2012-05-15 US disclosed
US-20110021764-A1 AZO PIGMENT, PIGMENT DISPERSION CONTAINING THE AZO PIGMENT, AND COLORING COMPOSITION FUJIFILM CORPORATION (JP) 2011-01-27 US disclosed