SCHEMBL4742276

SCHEMBL4742276

Cc1c(/N=N/c2c(C#N)cnn2-c2ncccn2)c(O)[nH]c(=O)c1C#N

nearest known ligand 0.41

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.41
MEN1 O00255 4/20 0.41
MAPT P10636 4/20 0.41
LMNA P02545 1/20 0.41
PHGDH O43175 1/20 0.38
USP2 O75604 1/20 0.35
RAB9A P51151 1/20 0.35
MCL1 Q07820 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
UPP1 Q16831 4/20 0.34
TDP1 Q9NUW8 1/20 0.33
PDE9A O76083 2/20 0.31
PIM1 P11309 1/20 0.31
KDM4D Q6B0I6 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4742242 0.85 IDO1 (0.38) KMT2AMEN1MAPTLMNAPHGDH
SCHEMBL4742259 0.82 MAPT (0.38) KMT2AMEN1MAPTLMNASMN1; SMN2
SCHEMBL4743198 0.82 MAPT (0.38) KMT2AMEN1MAPTLMNASMN1; SMN2
SCHEMBL4742312 0.75 MEN1 (0.37) KMT2AMEN1MAPTLMNASMN1; SMN2
SCHEMBL4742280 0.75 RXRA (0.32) KMT2ALMNATDP1
SCHEMBL4742563 0.73 MAPT (0.36) KMT2AMEN1MAPTLMNARAB9A
SCHEMBL4742613 0.72 HTT (0.35) KMT2AMEN1MAPTLMNASMN1; SMN2
SCHEMBL4781146 0.72 MAPT (0.40) KMT2AMEN1MAPTLMNASMN1; SMN2
SCHEMBL4742610 0.72
SCHEMBL10101932 0.72 ALDH1A1 (0.32) RAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8177861-B2 AZO pigment, pigment dispersion containing the AZO pigment, and coloring composition FUJIFILM CORPORATION (JP) 2012-05-15 US disclosed
US-8177861-B2 AZO pigment, pigment dispersion containing the AZO pigment, and coloring composition FUJIFILM CORPORATION (JP) 2012-05-15 US disclosed
US-20110021764-A1 AZO PIGMENT, PIGMENT DISPERSION CONTAINING THE AZO PIGMENT, AND COLORING COMPOSITION FUJIFILM CORPORATION (JP) 2011-01-27 US disclosed
US-20110021764-A1 AZO PIGMENT, PIGMENT DISPERSION CONTAINING THE AZO PIGMENT, AND COLORING COMPOSITION FUJIFILM CORPORATION (JP) 2011-01-27 US disclosed