SCHEMBL4742315

SCHEMBL4742315

Cc1c(/N=N/c2ncnn2-c2nc(N)nc(N)n2)c(O)n(C)c(=O)c1C#N

nearest known ligand 0.40

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.40
MEN1 O00255 5/20 0.40
KMT2A Q03164 5/20 0.40
ALDH1A1 P00352 4/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
KDM4E B2RXH2 3/20 0.37
PKM P14618 1/20 0.33
GAA P10253 1/20 0.33
TDP1 Q9NUW8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4781146 0.73 MAPT (0.40) MAPTMEN1KMT2AALDH1A1SMN1; SMN2
SCHEMBL10106725 0.71 POLB (0.35) MAPTKMT2ATDP1
SCHEMBL4742259 0.69 MAPT (0.38) MAPTMEN1KMT2AALDH1A1SMN1; SMN2
SCHEMBL4743198 0.69 MAPT (0.38) MAPTMEN1KMT2AALDH1A1SMN1; SMN2
SCHEMBL10184550 0.68 MAPT (0.65) MAPTMEN1KMT2AALDH1A1SMN1; SMN2
SCHEMBL29265299 0.66 MAPT (0.47) MAPTMEN1KMT2AALDH1A1SMN1; SMN2
SCHEMBL29265298 0.66 MAPT (0.47) MAPTMEN1KMT2AALDH1A1SMN1; SMN2
SCHEMBL11058970 0.65 KMT2A (0.56) MAPTMEN1KMT2AALDH1A1SMN1; SMN2
SCHEMBL11058973 0.65 KMT2A (0.56) MAPTMEN1KMT2AALDH1A1SMN1; SMN2
SCHEMBL18335256 0.65 MAPT (0.54) MAPTMEN1KMT2AALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8177861-B2 AZO pigment, pigment dispersion containing the AZO pigment, and coloring composition FUJIFILM CORPORATION (JP) 2012-05-15 US disclosed
US-8177861-B2 AZO pigment, pigment dispersion containing the AZO pigment, and coloring composition FUJIFILM CORPORATION (JP) 2012-05-15 US disclosed
US-20110021764-A1 AZO PIGMENT, PIGMENT DISPERSION CONTAINING THE AZO PIGMENT, AND COLORING COMPOSITION FUJIFILM CORPORATION (JP) 2011-01-27 US disclosed
US-20110021764-A1 AZO PIGMENT, PIGMENT DISPERSION CONTAINING THE AZO PIGMENT, AND COLORING COMPOSITION FUJIFILM CORPORATION (JP) 2011-01-27 US disclosed